An emerging hemorrhagic fever in China caused by a novel bunyavirus SFTSV

XiaoShuang S. Zhang, Yan Liu, Li Zhao, Bing Li, Hao Yu, HongLing L. Wen, Xue Jie Yu

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging hemorrhagic fever in rural areas of China and is caused by a new bunyavirus, SFTSV, named after the disease. The transmission vectors and animal hosts of SFTSV are unclear. Ticks are the most likely transmission vectors and domestic animals, including goats, dogs, and cattle, are potential amplifying hosts of SFTSV. The clinical symptoms of SFTS are nonspecific, but major symptoms include fever, gastrointestinal symptoms, myalgia, dizziness, joint pain, chills, and regional lymphadenopathy. The most common abnormalities in laboratory test results are thrombocytopenia (95%), leukocytopenia (86%), and elevated levels of serum alanine aminotransferase, aspartate aminotransferase, creatine kinase, and lactate dehydrogenase. The fatality rate for SFTS is 12% on average, and the annual incidence of the disease is approximately five per 100000 of the rural population.

Original languageEnglish (US)
Pages (from-to)697-700
Number of pages4
JournalScience China Life Sciences
Volume56
Issue number8
DOIs
StatePublished - Aug 2013

Fingerprint

Orthobunyavirus
thrombocytopenia
fever
China
Animals
Fever
Thrombocytopenia
animal
tick
rural population
signs and symptoms (animals and humans)
goat
Creatine Kinase
Aspartate Aminotransferases
abnormality
Alanine Transaminase
L-Lactate Dehydrogenase
cattle
serum
rural area

Keywords

  • bunyavirus
  • emerging infectious diseases
  • hemorrhagic fever
  • leukopenia
  • Phlebovirus
  • SFTSV
  • thrombocytopenia
  • tick

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Environmental Science(all)

Cite this

Zhang, X. S., Liu, Y., Zhao, L., Li, B., Yu, H., Wen, H. L., & Yu, X. J. (2013). An emerging hemorrhagic fever in China caused by a novel bunyavirus SFTSV. Science China Life Sciences, 56(8), 697-700. https://doi.org/10.1007/s11427-013-4518-9

An emerging hemorrhagic fever in China caused by a novel bunyavirus SFTSV. / Zhang, XiaoShuang S.; Liu, Yan; Zhao, Li; Li, Bing; Yu, Hao; Wen, HongLing L.; Yu, Xue Jie.

In: Science China Life Sciences, Vol. 56, No. 8, 08.2013, p. 697-700.

Research output: Contribution to journalArticle

Zhang, XS, Liu, Y, Zhao, L, Li, B, Yu, H, Wen, HL & Yu, XJ 2013, 'An emerging hemorrhagic fever in China caused by a novel bunyavirus SFTSV', Science China Life Sciences, vol. 56, no. 8, pp. 697-700. https://doi.org/10.1007/s11427-013-4518-9
Zhang, XiaoShuang S. ; Liu, Yan ; Zhao, Li ; Li, Bing ; Yu, Hao ; Wen, HongLing L. ; Yu, Xue Jie. / An emerging hemorrhagic fever in China caused by a novel bunyavirus SFTSV. In: Science China Life Sciences. 2013 ; Vol. 56, No. 8. pp. 697-700.
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