An epidemic of yellow fever in Central Brazil, 1972-1973. I. Epidemiological studies

F. P. Pinheiro, A. P A Travassos Da Rosa, M. A P Moraes, J. C. Almeida Neto, S. Camargo, J. P. Filgueiras

Research output: Contribution to journalArticle

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Abstract

An epidemic of jungle yellow fever occurred in Goias State, Brazil, between December 1972 and March 1973. Laboratory confirmed cases were observed in 36 counties located in the central and southern parts of the State. Seventy-one cases were proved, of which 44 were fatal. The diagnosis was made on the basis of pathology, serology, and virus isolation. Besides yellow fever, malaria and viral hepatitis were present, and in two fatal cases there was malarial pigment in the liver in addition to the specific lesions associated with yellow fever virus infection. The fact that male patients strikingly outnumbered females (9:1) and that young adults were predominantly affected indicates that transmission occurred mainly inside or adjacent to the forests. The lack of cases in urban areas can be attributed to the absence of Aedes aegypti in these areas. Yellow fever complement-fixing antibody in high titers was found in 18 of 1,201 (1.4%) persons living in eight counties of the affected area. This finding suggests that at least 21,000 persons out of the 1.5 million rural inhabitants of the three districts where the epidemic occurred had been infected by the virus. The epidemic subsided following an intensive vaccination campaign, and the last four cases were observed in March, 1973.

Original languageEnglish (US)
Pages (from-to)125-132
Number of pages8
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume27
Issue number1 I
StatePublished - 1978
Externally publishedYes

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Yellow Fever
Brazil
Epidemiologic Studies
Yellow fever virus
Viruses
Immunization Programs
Aedes
Virus Diseases
Serology
Hepatitis
Malaria
Young Adult
Pathology
Antibodies
Liver

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Pinheiro, F. P., Travassos Da Rosa, A. P. A., Moraes, M. A. P., Almeida Neto, J. C., Camargo, S., & Filgueiras, J. P. (1978). An epidemic of yellow fever in Central Brazil, 1972-1973. I. Epidemiological studies. American Journal of Tropical Medicine and Hygiene, 27(1 I), 125-132.

An epidemic of yellow fever in Central Brazil, 1972-1973. I. Epidemiological studies. / Pinheiro, F. P.; Travassos Da Rosa, A. P A; Moraes, M. A P; Almeida Neto, J. C.; Camargo, S.; Filgueiras, J. P.

In: American Journal of Tropical Medicine and Hygiene, Vol. 27, No. 1 I, 1978, p. 125-132.

Research output: Contribution to journalArticle

Pinheiro, FP, Travassos Da Rosa, APA, Moraes, MAP, Almeida Neto, JC, Camargo, S & Filgueiras, JP 1978, 'An epidemic of yellow fever in Central Brazil, 1972-1973. I. Epidemiological studies', American Journal of Tropical Medicine and Hygiene, vol. 27, no. 1 I, pp. 125-132.
Pinheiro FP, Travassos Da Rosa APA, Moraes MAP, Almeida Neto JC, Camargo S, Filgueiras JP. An epidemic of yellow fever in Central Brazil, 1972-1973. I. Epidemiological studies. American Journal of Tropical Medicine and Hygiene. 1978;27(1 I):125-132.
Pinheiro, F. P. ; Travassos Da Rosa, A. P A ; Moraes, M. A P ; Almeida Neto, J. C. ; Camargo, S. ; Filgueiras, J. P. / An epidemic of yellow fever in Central Brazil, 1972-1973. I. Epidemiological studies. In: American Journal of Tropical Medicine and Hygiene. 1978 ; Vol. 27, No. 1 I. pp. 125-132.
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