An influenza virus inhibitor that acts late in the replication cycle

G. Antonelli; F. Dianzani; D. H. Coppenhaver; S. Baron; P. Calandra; G. Folchitto

doi:10.1128/AAC.29.1.49

An influenza virus inhibitor that acts late in the replication cycle

G. Antonelli
, F. Dianzani
, D. H. Coppenhaver
, S. Baron
, P. Calandra
, G. Folchitto

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

An inhibitor which is active against influenza A virus was found in Neuramide, a complex tissue extract that is used as an anti-herpes zoster virus treatment. Kinetic studies showed that significant inhibition of virus production occurred when the inhibitor was added to infected cultures up to 5 h after virus penetration. Molecular sieving fractionation showed that the antiviral activity was contained in a low-molecular-weight fraction (molecular weight, <1,000).

Original language	English (US)
Pages (from-to)	49-51
Number of pages	3
Journal	Antimicrobial agents and chemotherapy
Volume	29
Issue number	1
DOIs	https://doi.org/10.1128/AAC.29.1.49
State	Published - 1986
Externally published	Yes

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

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10.1128/AAC.29.1.49

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abstract = "An inhibitor which is active against influenza A virus was found in Neuramide, a complex tissue extract that is used as an anti-herpes zoster virus treatment. Kinetic studies showed that significant inhibition of virus production occurred when the inhibitor was added to infected cultures up to 5 h after virus penetration. Molecular sieving fractionation showed that the antiviral activity was contained in a low-molecular-weight fraction (molecular weight, <1,000).",

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AU - Coppenhaver, D. H.

AU - Baron, S.

AU - Calandra, P.

AU - Folchitto, G.

PY - 1986

Y1 - 1986

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An influenza virus inhibitor that acts late in the replication cycle

Abstract

ASJC Scopus subject areas

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