An objective method for assessing graded electrically evoked afferent activity in humans

Carl G. Kukulka; David A. Brown; Margaret M. Weightman

doi:10.1016/0168-5597(91)90018-S

An objective method for assessing graded electrically evoked afferent activity in humans

Carl G. Kukulka, David A. Brown, Margaret M. Weightman

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

A problem arises in human sensorimotor studies when attempts are made to equate the intensity of electrical stimulation of a peripheral nerve with the amount of afferent activity generated. Results presented here reveal that sural recruitment curves exhibit large session to session differences both within and among subjects. These differences hinder the prediction of afferent activation based solely upon stimulus intensity. An alternative method based upon measurement of the evoked potentials is described for improving on these predictions. Sural nerve stimulation is used to demonstrate this method, but the method should be applicable wherever a peripheral nerve is accessible for electrical stimulation and evoked recordings.

Original language	English (US)
Pages (from-to)	312-318
Number of pages	7
Journal	Electroencephalography and Clinical Neurophysiology/ Evoked Potentials
Volume	81
Issue number	4
DOIs	https://doi.org/10.1016/0168-5597(91)90018-S
State	Published - Aug 1991
Externally published	Yes

Keywords

Evoked potentials
Sural nerve

ASJC Scopus subject areas

General Neuroscience
Clinical Neurology

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10.1016/0168-5597(91)90018-S

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title = "An objective method for assessing graded electrically evoked afferent activity in humans",

abstract = "A problem arises in human sensorimotor studies when attempts are made to equate the intensity of electrical stimulation of a peripheral nerve with the amount of afferent activity generated. Results presented here reveal that sural recruitment curves exhibit large session to session differences both within and among subjects. These differences hinder the prediction of afferent activation based solely upon stimulus intensity. An alternative method based upon measurement of the evoked potentials is described for improving on these predictions. Sural nerve stimulation is used to demonstrate this method, but the method should be applicable wherever a peripheral nerve is accessible for electrical stimulation and evoked recordings.",

keywords = "Evoked potentials, Sural nerve",

author = "Kukulka, {Carl G.} and Brown, {David A.} and Weightman, {Margaret M.}",

note = "Funding Information: 1 Support for this work was provided by NIH Grant NS-24991.",

year = "1991",

month = aug,

doi = "10.1016/0168-5597(91)90018-S",

language = "English (US)",

volume = "81",

pages = "312--318",

journal = "Electroencephalography and Clinical Neurophysiology/ Evoked Potentials",

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T1 - An objective method for assessing graded electrically evoked afferent activity in humans

AU - Kukulka, Carl G.

AU - Brown, David A.

AU - Weightman, Margaret M.

N1 - Funding Information: 1 Support for this work was provided by NIH Grant NS-24991.

PY - 1991/8

Y1 - 1991/8

N2 - A problem arises in human sensorimotor studies when attempts are made to equate the intensity of electrical stimulation of a peripheral nerve with the amount of afferent activity generated. Results presented here reveal that sural recruitment curves exhibit large session to session differences both within and among subjects. These differences hinder the prediction of afferent activation based solely upon stimulus intensity. An alternative method based upon measurement of the evoked potentials is described for improving on these predictions. Sural nerve stimulation is used to demonstrate this method, but the method should be applicable wherever a peripheral nerve is accessible for electrical stimulation and evoked recordings.

AB - A problem arises in human sensorimotor studies when attempts are made to equate the intensity of electrical stimulation of a peripheral nerve with the amount of afferent activity generated. Results presented here reveal that sural recruitment curves exhibit large session to session differences both within and among subjects. These differences hinder the prediction of afferent activation based solely upon stimulus intensity. An alternative method based upon measurement of the evoked potentials is described for improving on these predictions. Sural nerve stimulation is used to demonstrate this method, but the method should be applicable wherever a peripheral nerve is accessible for electrical stimulation and evoked recordings.

KW - Evoked potentials

KW - Sural nerve

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AN - SCOPUS:0025996789

SN - 0168-5597

VL - 81

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EP - 318

JO - Electroencephalography and Clinical Neurophysiology/ Evoked Potentials

JF - Electroencephalography and Clinical Neurophysiology/ Evoked Potentials

IS - 4

ER -

An objective method for assessing graded electrically evoked afferent activity in humans

Abstract

Keywords

ASJC Scopus subject areas

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