Analysis of ehrlichial p28 gene expression in a murine model of persistent infection.

Patricia A. Crocquet-Valdes; Jere W. McBride; Hui Min Feng; Nahed Ismail; Melissa A. Small; Xue Jie Yu; David H. Walker

doi:10.1196/annals.1355.076

Analysis of ehrlichial p28 gene expression in a murine model of persistent infection.

Patricia A. Crocquet-Valdes, Jere W. McBride, Hui Min Feng, Nahed Ismail, Melissa A. Small, Xue Jie Yu, David H. Walker

Pathology

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Historically, ehrlichioses were tick-borne diseases of veterinary medical importance and are now important emerging infectious diseases in humans. p28s are encoded by multigene families with ORFs tandemly arranged with intergenic spaces of variable lengths. We reported initial sequencing of the Ehrlichia muris p28 locus. A model of persistent infection was described and provided tools for study of persistent ehrlichial infection. We completed the sequence of the E. muris p28 locus and examined mRNA expression.

Original language	English (US)
Pages (from-to)	420-424
Number of pages	5
Journal	Annals of the New York Academy of Sciences
Volume	1063
DOIs	https://doi.org/10.1196/annals.1355.076
State	Published - Dec 2005

ASJC Scopus subject areas

General Neuroscience
General Biochemistry, Genetics and Molecular Biology
History and Philosophy of Science

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abstract = "Historically, ehrlichioses were tick-borne diseases of veterinary medical importance and are now important emerging infectious diseases in humans. p28s are encoded by multigene families with ORFs tandemly arranged with intergenic spaces of variable lengths. We reported initial sequencing of the Ehrlichia muris p28 locus. A model of persistent infection was described and provided tools for study of persistent ehrlichial infection. We completed the sequence of the E. muris p28 locus and examined mRNA expression.",

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AU - McBride, Jere W.

AU - Feng, Hui Min

AU - Ismail, Nahed

AU - Small, Melissa A.

AU - Yu, Xue Jie

AU - Walker, David H.

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AB - Historically, ehrlichioses were tick-borne diseases of veterinary medical importance and are now important emerging infectious diseases in humans. p28s are encoded by multigene families with ORFs tandemly arranged with intergenic spaces of variable lengths. We reported initial sequencing of the Ehrlichia muris p28 locus. A model of persistent infection was described and provided tools for study of persistent ehrlichial infection. We completed the sequence of the E. muris p28 locus and examined mRNA expression.

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Analysis of ehrlichial p28 gene expression in a murine model of persistent infection.

Abstract

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