Analysis of sputum/tracheal aspirate and nasopharyngeal samples for SARS-CoV-2 detection by laboratory-developed test and Panther Fusion system

Phyu M. Thwe, Ping Ren

Research output: Contribution to journalArticlepeer-review

Abstract

In this study, 127 sputum/tracheal aspirate specimens were evaluated by a laboratory-developed real-time RT-PCR method and Fusion SARS-CoV-2 assay. These specimens were collected from the patients who have nasopharyngeal swab (NPS) samples being used for SARS-CoV-2 detection previously or simultaneously. The overall agreement was 96% between the lower respiratory tract (LRT) and NPS samples, suggesting that LRT specimens could be an option for patients who develop a productive cough or those receiving invasive mechanical ventilation.

Original languageEnglish (US)
Article number115228
JournalDiagnostic Microbiology and Infectious Disease
Volume99
Issue number1
DOIs
StatePublished - Jan 2021

Keywords

  • COVID-19
  • Lower respiratory tract
  • Nasopharyngeal swab sample
  • SARS-CoV-2
  • Sputum
  • Tracheal aspirate

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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