Analysis of the heterogeneity of T-cell responses in human leishmaniasis

Peter Melby, D. L. Sacks

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

In summary, we have found the T-cell in active human leishmaniasis to be profoundly heterogeneous, with no evidence of an 'immunodominant' antigen or antigens. The T-cell responses to each of these antigens are likely to contribute to resolution of active infection, but identification of individual antigens that can confer protective immunity will be most challenging.

Original languageEnglish (US)
Pages (from-to)768-771
Number of pages4
JournalAnnales de l'Institut Pasteur - Immunology
Volume138
Issue number5
StatePublished - 1987
Externally publishedYes

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Leishmaniasis
T-Lymphocytes
Antigens
Immunodominant Epitopes
Immunity
Infection

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Analysis of the heterogeneity of T-cell responses in human leishmaniasis. / Melby, Peter; Sacks, D. L.

In: Annales de l'Institut Pasteur - Immunology, Vol. 138, No. 5, 1987, p. 768-771.

Research output: Contribution to journalArticle

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