Android adiposity and lack of moderate and vigorous physical activity are associated with insulin resistance and diabetes in aging adults

Mark D. Peterson, Soham Al Snih al snih, José A. Serra-Rexach, C. F. Charles Burant

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background. Physical inactivity and excess adiposity are thought to be interdependent "lifestyle" factors and thus, many older adults are at exaggerated risk for preventable diseases. The purposes of this study were to determine the degree of discordance between body mass index (BMI) and adiposity among adults older than 50 years, and to determine the extent to which direct measures of adiposity, and objectively measured sedentary behavior (SB) and physical activity (PA) are associated with insulin resistance (IR) or diabetes. Methods. A population representative sample of 2,816 individuals, aged 50â€"85 years, was included from the combined 2003â€"2006 National Health and Nutrition Examination Survey (NHANES) datasets. BMI, percent body fat (%BF) and android adiposity as determined by dual energy x-ray absorptiometry, objectively measured SB and PA, established markers of cardiometabolic risk, IR, and type 2 diabetes were analyzed. Results. Approximately 50% of the men and 64% of the women who were normal weight according to BMI had excessive %BF. Adults with the least SB and greatest moderate and vigorous PA exhibited the healthiest cardiometabolic profiles, whereas adults with the greatest SB and lowest activity had highest risk. Greater android adiposity stores were robustly associated with IR or diabetes in all adults, independent of SB and activity. Among men, less moderate-to-vigorous PA was associated with IR or diabetes; whereas among women, less lifestyle moderate activity was associated with IR or diabetes. Conclusions. Android adiposity and low moderate and vigorous PA are the strongest predictors of IR or diabetes among aging adults.

Original languageEnglish (US)
Pages (from-to)1009-1017
Number of pages9
JournalJournals of Gerontology - Series A Biological Sciences and Medical Sciences
Volume70
Issue number8
DOIs
StatePublished - 2015

Fingerprint

Adiposity
Insulin Resistance
Exercise
Body Mass Index
Life Style
Nutrition Surveys
Type 2 Diabetes Mellitus
Adipose Tissue
X-Rays
Weights and Measures
Population

Keywords

  • Android adiposity
  • Diabetes
  • Insulin resistance
  • MVPA
  • Obesity
  • Sedentary behavior

ASJC Scopus subject areas

  • Aging
  • Geriatrics and Gerontology

Cite this

Android adiposity and lack of moderate and vigorous physical activity are associated with insulin resistance and diabetes in aging adults. / Peterson, Mark D.; Al Snih al snih, Soham; Serra-Rexach, José A.; Charles Burant, C. F.

In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences, Vol. 70, No. 8, 2015, p. 1009-1017.

Research output: Contribution to journalArticle

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