Antenatal antecedents and the impact of obstetric care in the etiology of cerebral palsy

Shannon M. Clark, Labib M. Ghulmiyyah, Gary D.V. Hankins

Research output: Contribution to journalArticle

38 Scopus citations

Abstract

Cerebral palsy (CP) affects 2/1000 live-born children. Multiple antenatal factors, including preterm delivery, low birth weight, infection/inflammation, multiple gestation, and other pregnancy complications, are mostly associated with CP in both the preterm and term infant, with birth asphyxia playing a minor role. Owing to the increasing survival of the very preterm and very low birth weight infant secondary to improvements in neonatal and obstetric care, the incidence of CP may be increasing. The focus of this paper is to explore antenatal antecedents as etiologies of CP and the impact of obstetric care on the prevention of CP.

Original languageEnglish (US)
Pages (from-to)775-786
Number of pages12
JournalClinical Obstetrics and Gynecology
Volume51
Issue number4
DOIs
StatePublished - Dec 1 2008

Keywords

  • Antenatal factors
  • Cerebral palsy
  • Infection
  • Pregnancy complications
  • Preterm delivery

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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