Abstract
The field of cysteinyl leukotriene research has moved forward considerably in the past two years. Significant recent advances have been made in three areas: genetic control of the cysteinyl leukotriene response, in which alterations in both the promoter region and in transcribed mRNA have been described; the mechanisms by which cysteinyl leukotrienes promote the development of inflammation; and extensions in the clinical arena that support broader positioning of leukotriene modifiers in the therapy of asthma and allergic diseases.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 230-234 |
| Number of pages | 5 |
| Journal | Current Opinion in Pharmacology |
| Volume | 1 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jun 1 2001 |
| Externally published | Yes |
Keywords
- Cysteinyl leukotrienes
- Eosinophils
- Genetics
- Immunology
- Leukotriene modifiers
- Molecular Medicine
- Pharmacology
ASJC Scopus subject areas
- Pharmacology
- Drug Discovery