Antibiotic prophylaxis in clean-contaminated head and neck oncologic surgery.

R. S. Weber, D. L. Callender

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

The use of antibiotic prophylaxis in head and neck oncologic surgery has greatly reduced the risk of postoperative wound infection and the corresponding increase in morbidity and health care costs. Conversely, inappropriate perioperative use of antibiotics increases costs and risk to patients. Antibiotic prophylaxis is beneficial only in clean-contaminated head and neck surgery; targets are the bacterial flora that commonly inhabit the skin and upper aerodigestive tract, with antibiotics effective against gram-positive aerobic organisms and anaerobic organisms providing the best coverage. Maximum efficacy is achieved with immediate preoperative and short-term (less than 48 hours) postoperative antimicrobial administration in adequate doses. Optimum benefit from prophylaxis in head and neck oncologic surgery depends on appropriate selection and administration of antibiotics in combination with sound, established surgical principles.

Original languageEnglish
Pages (from-to)16-20
Number of pages5
JournalThe Annals of otology, rhinology & laryngology. Supplement
Volume155
StatePublished - Jan 1992
Externally publishedYes

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Antibiotic Prophylaxis
Neck
Head
Anti-Bacterial Agents
Surgical Wound Infection
Health Care Costs
Morbidity
Costs and Cost Analysis
Skin

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Antibiotic prophylaxis in clean-contaminated head and neck oncologic surgery. / Weber, R. S.; Callender, D. L.

In: The Annals of otology, rhinology & laryngology. Supplement, Vol. 155, 01.1992, p. 16-20.

Research output: Contribution to journalArticle

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