Antibiotic use in Vietnamese hospitals

A multicenter point-prevalence study

Truong Anh Thu, Mahbubur Rahman, Susan Coffin, Md Harun-Or-Rashid, Junichi Sakamoto, Nguyen Viet Hung

    Research output: Contribution to journalArticle

    35 Citations (Scopus)

    Abstract

    Background: Inappropriate antibiotic prescribing appears to be common worldwide and is contributing to the selection of resistant organisms. This study examined the prevalence of antibiotic prescription and the appropriateness of indications for these prescriptions in 36 representative general hospitals across Vietnam. Methods: A point-prevalence study was performed between February and December 2008. All inpatients on the day of the survey were included in the analysis. Standard published guidelines were used to evaluate the appropriateness of indications for antibiotic prescription. Results: On the day of the study, 5,104 of 7,571 patients (67.4%) were receiving antibiotic therapy. The antibiotic prescription rate was highest in surgery wards (93.2%) and lowest in medical wards (48.2%). Of the 5,104 patients receiving antibiotics, the most commonly prescribed agents were cephalosporins (70.2%), penicillins (21.6%), and aminoglycosides (18.9%). Approximately one-third of the patients (1,573 of 5,104) had an inappropriate indication for prescription. Risk factors independently associated with inappropriate indication for antibiotic prescription were seen in hospitals at the national level, obstetrics and gynecology departments, and surgical wards. Conclusions: Our data indicate a high rate of antibiotic use in Vietnamese hospitals, and also a high prevalence of inappropriate indications for antibiotic prescriptions. These findings suggest important areas for intervention and implementation of antibiotic stewardship policies in Vietnamese hospitals.

    Original languageEnglish (US)
    Pages (from-to)840-844
    Number of pages5
    JournalAmerican Journal of Infection Control
    Volume40
    Issue number9
    DOIs
    StatePublished - Nov 2012

    Fingerprint

    Cross-Sectional Studies
    Anti-Bacterial Agents
    Prescriptions
    Inappropriate Prescribing
    Hospital Obstetrics and Gynecology Department
    Vietnam
    Aminoglycosides
    Cephalosporins
    Gynecology
    General Hospitals
    Penicillins
    Inpatients
    Guidelines

    Keywords

    • Indication
    • Prescription
    • Prevalence
    • Vietnam

    ASJC Scopus subject areas

    • Infectious Diseases
    • Public Health, Environmental and Occupational Health
    • Epidemiology
    • Health Policy

    Cite this

    Thu, T. A., Rahman, M., Coffin, S., Harun-Or-Rashid, M., Sakamoto, J., & Hung, N. V. (2012). Antibiotic use in Vietnamese hospitals: A multicenter point-prevalence study. American Journal of Infection Control, 40(9), 840-844. https://doi.org/10.1016/j.ajic.2011.10.020

    Antibiotic use in Vietnamese hospitals : A multicenter point-prevalence study. / Thu, Truong Anh; Rahman, Mahbubur; Coffin, Susan; Harun-Or-Rashid, Md; Sakamoto, Junichi; Hung, Nguyen Viet.

    In: American Journal of Infection Control, Vol. 40, No. 9, 11.2012, p. 840-844.

    Research output: Contribution to journalArticle

    Thu, TA, Rahman, M, Coffin, S, Harun-Or-Rashid, M, Sakamoto, J & Hung, NV 2012, 'Antibiotic use in Vietnamese hospitals: A multicenter point-prevalence study', American Journal of Infection Control, vol. 40, no. 9, pp. 840-844. https://doi.org/10.1016/j.ajic.2011.10.020
    Thu, Truong Anh ; Rahman, Mahbubur ; Coffin, Susan ; Harun-Or-Rashid, Md ; Sakamoto, Junichi ; Hung, Nguyen Viet. / Antibiotic use in Vietnamese hospitals : A multicenter point-prevalence study. In: American Journal of Infection Control. 2012 ; Vol. 40, No. 9. pp. 840-844.
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