Antigenic and genetic properties of viruses linked to hemorrhagic fever with renal syndrome

C. S. Schmaljohn, S. E. Hasty, J. M. Dalrymple, James LeDuc, H. W. Lee, C. H. Von Bonsdorff, M. Brummer-Korvenkontio, A. Vaheri, T. F. Tsai, H. L. Regnery, D. Goldgaber, P. W. Lee

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Abstract

Hemorrhagic fever with renal syndrome (HFRS) comprises a variety of clinically similar diseases of viral etiology that are endemic to and sporadically epidemic throughout the Eurasian continent and Japan. Although HFRS has not been reported in North America, viruses that are antigenically similar to HFRS agents were recently isolated from rodents in the United States. Examination and comparison of eight representative isolates from endemic disease areas and from regions with no known associated HFRS indicate that these viruses represent a new and unique group that constitutes a separate genus in the Bunyaviridae family of animal viruses.

Original languageEnglish (US)
Pages (from-to)1041-1044
Number of pages4
JournalScience
Volume227
Issue number4690
StatePublished - 1985
Externally publishedYes

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Cite this

Schmaljohn, C. S., Hasty, S. E., Dalrymple, J. M., LeDuc, J., Lee, H. W., Von Bonsdorff, C. H., Brummer-Korvenkontio, M., Vaheri, A., Tsai, T. F., Regnery, H. L., Goldgaber, D., & Lee, P. W. (1985). Antigenic and genetic properties of viruses linked to hemorrhagic fever with renal syndrome. Science, 227(4690), 1041-1044.