Antigenic and genetic properties of viruses linked to hemorrhagic fever with renal syndrome

C. S. Schmaljohn; S. E. Hasty; J. M. Dalrymple; J. W. LeDuc; H. W. Lee; C. H. Von Bonsdorff; M. Brummer-Korvenkontio; A. Vaheri; T. F. Tsai; H. L. Regnery; D. Goldgaber; P. W. Lee

doi:10.1126/science.2858126

Antigenic and genetic properties of viruses linked to hemorrhagic fever with renal syndrome

C. S. Schmaljohn, S. E. Hasty, J. M. Dalrymple, J. W. LeDuc, H. W. Lee, C. H. Von Bonsdorff, M. Brummer-Korvenkontio, A. Vaheri, T. F. Tsai, H. L. Regnery, D. Goldgaber, P. W. Lee

Research output: Contribution to journal › Article › peer-review

359 Scopus citations

Abstract

Hemorrhagic fever with renal syndrome (HFRS) comprises a variety of clinically similar diseases of viral etiology that are endemic to and sporadically epidemic throughout the Eurasian continent and Japan. Although HFRS has not been reported in North America, viruses that are antigenically similar to HFRS agents were recently isolated from rodents in the United States. Examination and comparison of eight representative isolates from endemic disease areas and from regions with no known associated HFRS indicate that these viruses represent a new and unique group that constitutes a separate genus in the Bunyaviridae family of animal viruses.

Original language	English (US)
Pages (from-to)	1041-1044
Number of pages	4
Journal	Science
Volume	227
Issue number	4690
DOIs	https://doi.org/10.1126/science.2858126
State	Published - 1985
Externally published	Yes

ASJC Scopus subject areas

General

Access to Document

10.1126/science.2858126

Cite this

@article{6db64a5e52724aab83f0b5590b7f552e,

title = "Antigenic and genetic properties of viruses linked to hemorrhagic fever with renal syndrome",

abstract = "Hemorrhagic fever with renal syndrome (HFRS) comprises a variety of clinically similar diseases of viral etiology that are endemic to and sporadically epidemic throughout the Eurasian continent and Japan. Although HFRS has not been reported in North America, viruses that are antigenically similar to HFRS agents were recently isolated from rodents in the United States. Examination and comparison of eight representative isolates from endemic disease areas and from regions with no known associated HFRS indicate that these viruses represent a new and unique group that constitutes a separate genus in the Bunyaviridae family of animal viruses.",

author = "Schmaljohn, {C. S.} and Hasty, {S. E.} and Dalrymple, {J. M.} and LeDuc, {J. W.} and Lee, {H. W.} and {Von Bonsdorff}, {C. H.} and M. Brummer-Korvenkontio and A. Vaheri and Tsai, {T. F.} and Regnery, {H. L.} and D. Goldgaber and Lee, {P. W.}",

year = "1985",

doi = "10.1126/science.2858126",

language = "English (US)",

volume = "227",

pages = "1041--1044",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "4690",

}

TY - JOUR

T1 - Antigenic and genetic properties of viruses linked to hemorrhagic fever with renal syndrome

AU - Schmaljohn, C. S.

AU - Hasty, S. E.

AU - Dalrymple, J. M.

AU - LeDuc, J. W.

AU - Lee, H. W.

AU - Von Bonsdorff, C. H.

AU - Brummer-Korvenkontio, M.

AU - Vaheri, A.

AU - Tsai, T. F.

AU - Regnery, H. L.

AU - Goldgaber, D.

AU - Lee, P. W.

PY - 1985

Y1 - 1985

N2 - Hemorrhagic fever with renal syndrome (HFRS) comprises a variety of clinically similar diseases of viral etiology that are endemic to and sporadically epidemic throughout the Eurasian continent and Japan. Although HFRS has not been reported in North America, viruses that are antigenically similar to HFRS agents were recently isolated from rodents in the United States. Examination and comparison of eight representative isolates from endemic disease areas and from regions with no known associated HFRS indicate that these viruses represent a new and unique group that constitutes a separate genus in the Bunyaviridae family of animal viruses.

AB - Hemorrhagic fever with renal syndrome (HFRS) comprises a variety of clinically similar diseases of viral etiology that are endemic to and sporadically epidemic throughout the Eurasian continent and Japan. Although HFRS has not been reported in North America, viruses that are antigenically similar to HFRS agents were recently isolated from rodents in the United States. Examination and comparison of eight representative isolates from endemic disease areas and from regions with no known associated HFRS indicate that these viruses represent a new and unique group that constitutes a separate genus in the Bunyaviridae family of animal viruses.

UR - http://www.scopus.com/inward/record.url?scp=0021987698&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021987698&partnerID=8YFLogxK

U2 - 10.1126/science.2858126

DO - 10.1126/science.2858126

M3 - Article

C2 - 2858126

AN - SCOPUS:0021987698

SN - 0036-8075

VL - 227

SP - 1041

EP - 1044

JO - Science

JF - Science

IS - 4690

ER -

Antigenic and genetic properties of viruses linked to hemorrhagic fever with renal syndrome

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this