Antineutrophil cytoplasmic antibodies negative levamisole-induced leukocytoclastic vasculitis: a presumed case and literature review

Daniel Kunzler, Lauren Lagrimas, Thiennga Vo, Andrew DeCrescenzo, Kyle Kaltwasser, Janice Wilson

Research output: Contribution to journalArticle

2 Scopus citations


Levamisole-contaminated cocaine toxicity is a serious emerging public health concern, and providers should be aware of its presentation and management. Most cases of levamisole-induced vasculitis/vasculopathy (LIV) are associated with high antineutrophil cytoplasmic antibodies (ANCA). We describe a unique case of a cocaine user who presented with an acute purpuric eruption and negative ANCA laboratory findings. A brief clinical overview of LIV, spanning from patient presentation to treatment, is provided. In addition, we present a summary of all cases of ANCA-negative vasculitis identified via a PubMed literature review.

Original languageEnglish (US)
Pages (from-to)1411-1416
Number of pages6
JournalInternational Journal of Dermatology
Issue number12
StatePublished - Dec 1 2018


ASJC Scopus subject areas

  • Dermatology

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