Antineutrophil cytoplasmic antibodies negative levamisole-induced leukocytoclastic vasculitis: a presumed case and literature review

Daniel Kunzler, Lauren Lagrimas, Thiennga Vo, Andrew DeCrescenzo, Kyle Kaltwasser, Janice Wilson

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Levamisole-contaminated cocaine toxicity is a serious emerging public health concern, and providers should be aware of its presentation and management. Most cases of levamisole-induced vasculitis/vasculopathy (LIV) are associated with high antineutrophil cytoplasmic antibodies (ANCA). We describe a unique case of a cocaine user who presented with an acute purpuric eruption and negative ANCA laboratory findings. A brief clinical overview of LIV, spanning from patient presentation to treatment, is provided. In addition, we present a summary of all cases of ANCA-negative vasculitis identified via a PubMed literature review.

Original languageEnglish (US)
Pages (from-to)1411-1416
Number of pages6
JournalInternational Journal of Dermatology
Volume57
Issue number12
DOIs
StatePublished - Dec 1 2018

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Levamisole
Antineutrophil Cytoplasmic Antibodies
Vasculitis
Cocaine
PubMed
Public Health
Erythema elevatum diutinum
Therapeutics

ASJC Scopus subject areas

  • Dermatology

Cite this

Antineutrophil cytoplasmic antibodies negative levamisole-induced leukocytoclastic vasculitis : a presumed case and literature review. / Kunzler, Daniel; Lagrimas, Lauren; Vo, Thiennga; DeCrescenzo, Andrew; Kaltwasser, Kyle; Wilson, Janice.

In: International Journal of Dermatology, Vol. 57, No. 12, 01.12.2018, p. 1411-1416.

Research output: Contribution to journalArticle

Kunzler, Daniel ; Lagrimas, Lauren ; Vo, Thiennga ; DeCrescenzo, Andrew ; Kaltwasser, Kyle ; Wilson, Janice. / Antineutrophil cytoplasmic antibodies negative levamisole-induced leukocytoclastic vasculitis : a presumed case and literature review. In: International Journal of Dermatology. 2018 ; Vol. 57, No. 12. pp. 1411-1416.
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