TY - JOUR
T1 - Antioxidant effect of far infrared radiation produced by bioceramics in individuals with intermittent claudication
T2 - A randomized, controlled pilot study
AU - da Silva, Fábio Goulart
AU - Herr, Gerli Elenise Gehrke
AU - Cidral-Filho, Francisco José
AU - Petronilho, Fabricia
AU - Danielski, Lucineia Gainski
AU - Florentino, Drielly
AU - Bobinski, Franciane
AU - Ludtke, Daniela Dero
AU - Vieira, Cintia
AU - Martins, Daniel Fernandes
AU - Winkelmann, Eliane Roseli
N1 - Publisher Copyright:
© 2019, InnoVision Communications. All rights reserved.
PY - 2019/11
Y1 - 2019/11
N2 - Background • Biomedical research has recently incorporated bioceramics applications into new health care approaches. Objective • This study evaluated the effect of far infrared-emitting bioceramics wraps in the treatment of intermittent claudication. Methods • This is a randomized double-blind placebo-controlled pilot study. Thirty-five patients met the criteria and were randomized into either control (placebo wraps) or bioceramics group (far infrared emitting-ceramics wraps) and assessed over a 90-day period for the following outcomes: six-minute walk test (6MWT), ankle-brachial index (ABI), Flow-mediated arterial dilation (FMD), quality of life and claudication. Oxidative stress and inflammatory biomarkers were measured in plasma of patients. Results • Intervention induced a decrease in oxidative stress, with significant lower levels of reactive substances to thiobarbituric acid (TBARS), as well as increase in superoxide dismutase and catalase enzyme activities. There was an increase in the environment subscale of the quality of life questionnaire. No statistically significant differences were found in the inflammatory cytokines, 6MWT, ABI and FMV evaluations. Conclusions • In Sum, FIR treatment improved oxidative stress profile and quality-of-life of patients with intermittent claudication. The study was registered into the ensaiosclinicos.gov.br (Registro Brasileiro de Ensaios Clínicos [ReBEC]) (RBR-7nr6sy register number).
AB - Background • Biomedical research has recently incorporated bioceramics applications into new health care approaches. Objective • This study evaluated the effect of far infrared-emitting bioceramics wraps in the treatment of intermittent claudication. Methods • This is a randomized double-blind placebo-controlled pilot study. Thirty-five patients met the criteria and were randomized into either control (placebo wraps) or bioceramics group (far infrared emitting-ceramics wraps) and assessed over a 90-day period for the following outcomes: six-minute walk test (6MWT), ankle-brachial index (ABI), Flow-mediated arterial dilation (FMD), quality of life and claudication. Oxidative stress and inflammatory biomarkers were measured in plasma of patients. Results • Intervention induced a decrease in oxidative stress, with significant lower levels of reactive substances to thiobarbituric acid (TBARS), as well as increase in superoxide dismutase and catalase enzyme activities. There was an increase in the environment subscale of the quality of life questionnaire. No statistically significant differences were found in the inflammatory cytokines, 6MWT, ABI and FMV evaluations. Conclusions • In Sum, FIR treatment improved oxidative stress profile and quality-of-life of patients with intermittent claudication. The study was registered into the ensaiosclinicos.gov.br (Registro Brasileiro de Ensaios Clínicos [ReBEC]) (RBR-7nr6sy register number).
UR - http://www.scopus.com/inward/record.url?scp=85078825487&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85078825487&partnerID=8YFLogxK
M3 - Article
C2 - 32006455
AN - SCOPUS:85078825487
SN - 1078-6791
VL - 25
SP - 34
EP - 43
JO - Alternative therapies in health and medicine
JF - Alternative therapies in health and medicine
IS - 6
ER -