Anything You Can Do I Can Do Better

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Newly introduced drugs or treatments may not be substantively more effective than current therapies, but these drugs or treatments may have distinct advantages in terms of lower costs or fewer or less severe side effects. Demonstrating the utility of a novel treatment is thus unlike usual hypothesis testing, in which researchers seek to prove that treatments differ (i.e., that one treatment is better than another). Instead, researchers must prove that the treatments are equivalent in effectiveness (i.e., that the treatments do not differ). I discuss here how to execute this type of study: the non-inferiority study.

Original languageEnglish (US)
Pages (from-to)252-253
Number of pages2
JournalJournal of Foot and Ankle Surgery
Issue number2
StatePublished - Mar 2014
Externally publishedYes


  • Equivalence testing
  • Non-inferiority testing

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine


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