Aortic atherosclerosis in exotic avians

Federico Bohorquez, Clarke Stout

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Spontaneous arterial disease is documented in 14 exotic avian orders, and contrasted with that previously found in 333 mammals from the Oklahoma City Zoo. Arteriosclerosis, primarily fatty streaks and fibrous plaques, was noted in 65 (90%) of the 72 birds examined. True atheromata with central necrosis and foci of calcification, often containing doubly refractile cystals, were very common, being observed in 24% of the birds, as opposed to 1% of the hoofed mammals, 3% of the nonhuman primates, 10% of the exotic mammals and none of the carnivores or pinnipeds. Medial degeneration was seen in 6 birds, predominantly the large, nonflying types, and was closely allied to intimal disease, as opposed to medial disease in mammals, which is not related to intimal disease. Atheromatous plaques were noted in the penguins, previously thought to have species-resistance to atherosclerosis in spite of elevated serum cholesterol levels. The carnivorous birds exhibited a high incidence of arterial disease with extensive lipid deposition, in marked contrast to the lipid-poor lesions characteristic of the carnivorous mammals. The relatively high blood pressure and serum cholesterol levels of birds are felt to be responsible for the high incidence of atherosclerosis observed. The paucity of mural thrombi in birds may explain the absence of ischemic complications in the face of rather extensive atherosclerosis.

Original languageEnglish (US)
Pages (from-to)261-273
Number of pages13
JournalExperimental and Molecular Pathology
Volume17
Issue number3
DOIs
StatePublished - 1972

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Birds
Mammals
Atherosclerosis
Tunica Intima
Atherosclerotic Plaques
Pinnipedia
Cholesterol
Spheniscidae
Lipids
Arteriosclerosis
Incidence
Blood pressure
Hypercholesterolemia
Serum
Primates
Thrombosis
Necrosis
Hypertension

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Molecular Biology
  • Pathology and Forensic Medicine

Cite this

Aortic atherosclerosis in exotic avians. / Bohorquez, Federico; Stout, Clarke.

In: Experimental and Molecular Pathology, Vol. 17, No. 3, 1972, p. 261-273.

Research output: Contribution to journalArticle

Bohorquez, Federico ; Stout, Clarke. / Aortic atherosclerosis in exotic avians. In: Experimental and Molecular Pathology. 1972 ; Vol. 17, No. 3. pp. 261-273.
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