Apparatus and method for interfacing capillary electrophoresis and chemiluminescence nitrogen detection for the analysis of nitrogen-containing compounds

A. A. Mohammad, E. Fujinari, Anthony Okorodudu, J. R. Petersen

Research output: Contribution to journalArticle

10 Scopus citations


We have developed an interface that allows the specific detection of nitrogen-containing compounds by using a chemiluminescence nitrogen detector. The feasibility of using this interface was demonstrated by separating and detecting two nitrogen-containing compounds, p-aminosalicylic acid and l- phenylalanine. Although baseline separation was achieved, the theoretical plates were lower when compared to UV detection (25 000 vs. ~85 000). A sensitivity of 75 ng (~500 pmol) per injection was achieved with this system which is adequate for pharmaceutical and biotech applications.

Original languageEnglish (US)
Pages (from-to)121-125
Number of pages5
JournalJournal of Chromatography A
Issue number1
StatePublished - Jan 28 2000



  • Aminosalicylic acid
  • CE-chemiluminescence nitrogen detection
  • Detection, electrophoresis
  • Instrumentation
  • Interfaces
  • Phenylalanine

ASJC Scopus subject areas

  • Analytical Chemistry

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