Application of kinetic principles to intravenous fluid therapy

Donald Prough, Kirk I. Brauer

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The clinical understanding of changes in plasma volume and other body water compartments induced by infusion of intravenous fluids has been poorly quantified. Recently, investigators have studied the effects of intravenous fluids on volume expansion using mathematic techniques similar to those used for pharmacokinetic analysis of drugs. Combining these techniques with traditional concepts regarding perioperative fluid therapy promises to increase the precision with which fluids are given before, during, and after surgery.

Original languageEnglish (US)
Pages (from-to)419-433
Number of pages15
JournalProblems in Anesthesia
Volume11
Issue number4
StatePublished - Oct 1999

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Body Water
Plasma Volume
Mathematics
Fluid Therapy
Intravenous Infusions
Pharmacokinetics
Research Personnel
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Application of kinetic principles to intravenous fluid therapy. / Prough, Donald; Brauer, Kirk I.

In: Problems in Anesthesia, Vol. 11, No. 4, 10.1999, p. 419-433.

Research output: Contribution to journalArticle

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