Application of optical coherence tomography for noninvasive blood glucose monitoring during hyperglycemia

Kirill V. Larin, Taras V. Ashitkov, Massoud Motamedi, Rinat Esenaliev

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Approximately 14 million people in the USA and more than 140 million people worldwide suffer from Diabetes Mellitus. The current glucose sensing technique involves a finger puncture several times a day to obtain a droplet of blood for chemical analysis. Recently we proposed to use optical coherence tomography (OCT) for continuous noninvasive blood glucose sensing through skin. In this paper we tested the OCT technique for noninvasive monitoring of blood glucose concentration in lip tissue of New Zealand rabbits and Yucatan micropigs during glucose clamping experiments. Obtained results show good agreement with results obtained hi skin studies, good correlation of changes in the OCT signal slope measured at the depth of 250 to 500 μm with changes in blood glucose concentration, and higher stability of the OCT data points than that obtained from skin.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsV.V. Tuchin
Pages294-298
Number of pages5
Volume5068
StatePublished - 2002
EventSaratov Fall Meeting 2002 Optical Technologies in Biophysics and Medicine IV - Saratov, Russian Federation
Duration: Oct 1 2002Oct 4 2002

Other

OtherSaratov Fall Meeting 2002 Optical Technologies in Biophysics and Medicine IV
CountryRussian Federation
CitySaratov
Period10/1/0210/4/02

Fingerprint

hyperglycemia
Optical tomography
glucose
blood
Glucose
Blood
tomography
Monitoring
Skin
diabetes mellitus
rabbits
New Zealand
Medical problems
chemical analysis
Tissue
slopes
Chemical analysis

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Larin, K. V., Ashitkov, T. V., Motamedi, M., & Esenaliev, R. (2002). Application of optical coherence tomography for noninvasive blood glucose monitoring during hyperglycemia. In V. V. Tuchin (Ed.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 5068, pp. 294-298)

Application of optical coherence tomography for noninvasive blood glucose monitoring during hyperglycemia. / Larin, Kirill V.; Ashitkov, Taras V.; Motamedi, Massoud; Esenaliev, Rinat.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / V.V. Tuchin. Vol. 5068 2002. p. 294-298.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Larin, KV, Ashitkov, TV, Motamedi, M & Esenaliev, R 2002, Application of optical coherence tomography for noninvasive blood glucose monitoring during hyperglycemia. in VV Tuchin (ed.), Proceedings of SPIE - The International Society for Optical Engineering. vol. 5068, pp. 294-298, Saratov Fall Meeting 2002 Optical Technologies in Biophysics and Medicine IV, Saratov, Russian Federation, 10/1/02.
Larin KV, Ashitkov TV, Motamedi M, Esenaliev R. Application of optical coherence tomography for noninvasive blood glucose monitoring during hyperglycemia. In Tuchin VV, editor, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 5068. 2002. p. 294-298
Larin, Kirill V. ; Ashitkov, Taras V. ; Motamedi, Massoud ; Esenaliev, Rinat. / Application of optical coherence tomography for noninvasive blood glucose monitoring during hyperglycemia. Proceedings of SPIE - The International Society for Optical Engineering. editor / V.V. Tuchin. Vol. 5068 2002. pp. 294-298
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