@inbook{57dae2117c864e738e1f2bbe6667c8eb,
title = "Applications of MALDI-MSI to pharmaceutical research",
abstract = "MALDI-MSI has been demonstrated to be a suitable technique in pharmaceutical research for providing information of the distribution of low molecular weight compounds such as drugs and their metabolites within whole-body tissue sections. Important ADME information can be determined by MALDI-MSI analysis of the distribution of drugs and metabolites in whole-body tissue sections taken from animals killed at a range of time points postdose. In this example we applied MALDI-MSI to the localization of a compound and its primary metabolite in whole-body mouse sections.",
keywords = "MALDI-MSI, drug and metabolite imaging, whole-body tissue imaging",
author = "Brendan Prideaux and Dieter Staab and Markus Stoeckli",
year = "2010",
doi = "10.1007/978-1-60761-746-4_23",
language = "English (US)",
isbn = "9781607617457",
series = "Methods in Molecular Biology",
pages = "405--413",
editor = "Stanislav Rubakhin and Jonathan Sweedler",
booktitle = "Mass Spectrometry Imaging",
}