Approach to Management of Recurrent Esophageal Squamous Papilloma

Esophageal squamous papilloma (ESP) is an uncommon, normally benign epithelial neoplasm with rare potential for malignant transformation. These lesions are oftentimes found incidentally on upper endoscopy and are typically managed with endoscopic excision, dissection, or ablation. However, there remains a paucity of published management guidelines in the current literature. We present a case of an older female who was found to have an extensive mid-esophageal ESP with recurrence despite endoscopic intervention. We highlight the multi-institutional management approach to her morphologically atypical ESP and the nuance involved in treating recurrent lesions of this type.