TY - JOUR
T1 - Araguari virus, a new member of the family Orthomyxoviridae
T2 - Serologic, ultrastructural, and molecular characterization
AU - Pinto Da Silva, Eliana V.
AU - Travassos Da Rosa, Amelia P.A.
AU - Nunes, Márcio R.T.
AU - Diniz, José A.P.
AU - Tesh, Robert B.
AU - Cruz, Ana C.R.
AU - Vieira, Conceição M.A.
AU - Vasconcelos, Pedro F.C.
N1 - Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2005/12
Y1 - 2005/12
N2 - This paper reports the results of serologic, structural, biochemical, and genetic studies indicating that Araguari virus, a previously unassigned viral agent, is a member of the family Orthomyxoviridae and genus Thogotovirus. Araguari virus has six RNA fragments; biologically, it shares several properties with other viruses in the family Orthomyxoviridae. Nucleotide sequencing of the RNA segments 4 (glycoprotein) and 5 (nucleoprotein) of Araguari virus aligned with the orthomyxoviruses, showing the closest relationship with Thogoto virus (sequence similarity = 61.9% and 69.1%, respectively, for glycoprotein and nucleoprotein), but also sharing a more distant similarity with Dhori and Influenza C viruses, especially for the glycoprotein gene. Based on these results, we propose that Araguari virus should be assigned as a new member of the family Orthomyxoviridae and genus Thogotovirus.
AB - This paper reports the results of serologic, structural, biochemical, and genetic studies indicating that Araguari virus, a previously unassigned viral agent, is a member of the family Orthomyxoviridae and genus Thogotovirus. Araguari virus has six RNA fragments; biologically, it shares several properties with other viruses in the family Orthomyxoviridae. Nucleotide sequencing of the RNA segments 4 (glycoprotein) and 5 (nucleoprotein) of Araguari virus aligned with the orthomyxoviruses, showing the closest relationship with Thogoto virus (sequence similarity = 61.9% and 69.1%, respectively, for glycoprotein and nucleoprotein), but also sharing a more distant similarity with Dhori and Influenza C viruses, especially for the glycoprotein gene. Based on these results, we propose that Araguari virus should be assigned as a new member of the family Orthomyxoviridae and genus Thogotovirus.
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U2 - 10.4269/ajtmh.2005.73.1050
DO - 10.4269/ajtmh.2005.73.1050
M3 - Article
C2 - 16354811
AN - SCOPUS:29844443758
SN - 0002-9637
VL - 73
SP - 1050
EP - 1058
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
IS - 6
ER -