Arthropod-borne viral infections associated with a fever outbreak in the Northern Province of Sudan

D. M. Watts, A. El-Tigani, B. A M Botros, A. W. Salib, J. G. Olson, M. McCarthy, Thomas Ksiazek

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

An outbreak of acute febrile illness occurred during August and September 1989 in the Northern Province of Sudan coinciding with a high population density of phlebotomine sandflies. An investigation was conducted to determine whether arboviruses were associated with human illness during this outbreak. Sera were obtained from 185 febrile individuals and tested for IgG and IgM antibody to selected arboviruses by enzyme immunoassay (EIA). The prevalence of IgG antibody was 59% for West Nile (WN), 53% for Sandfly Fever Sicilian (SFS), 32% for Sandfly Fever Naples (SFN), 39% for Yellow Fever (YF), 24% for dengue-2 (DEN-2), 23% for Rift Valley Fever (RVF), 12% for Chikungunya (CHIK) and 5% for Crimean-Congo haemorrhagic Fever (CCHF) viruses. Antibody prevalences tended to increase with age for WN and YF viruses. Antibody rates were about the same for males and females for most of the viruses tested. The prevalence of IgM antibody to SFN was 24% and reciprocal IgM titre exceeded 12 800 for some individuals suggesting that this virus was the cause of recent infection. The prevalence of IgM antibody for the other viruses did not exceed 5%. The study indicated that several arboviruses were endemic and some of them may have caused human disease ill the Northern Province of Sudan.

Original languageEnglish (US)
Pages (from-to)228-230
Number of pages3
JournalJournal of Tropical Medicine and Hygiene
Volume97
Issue number4
StatePublished - 1994
Externally publishedYes

Fingerprint

Sudan
Arthropods
Virus Diseases
Antibodies
arthropod
antibody
Disease Outbreaks
Phlebotomus Fever
Viruses
Fever
virus
Arboviruses
Immunoglobulin M
yellow fever
West Nile Fever
Crimean-Congo hemorrhagic fever virus
Immunoglobulin G
Rift Valley Fever
Yellow fever virus
Yellow Fever

Keywords

  • Arboviruses
  • Fever
  • Sudan

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Watts, D. M., El-Tigani, A., Botros, B. A. M., Salib, A. W., Olson, J. G., McCarthy, M., & Ksiazek, T. (1994). Arthropod-borne viral infections associated with a fever outbreak in the Northern Province of Sudan. Journal of Tropical Medicine and Hygiene, 97(4), 228-230.

Arthropod-borne viral infections associated with a fever outbreak in the Northern Province of Sudan. / Watts, D. M.; El-Tigani, A.; Botros, B. A M; Salib, A. W.; Olson, J. G.; McCarthy, M.; Ksiazek, Thomas.

In: Journal of Tropical Medicine and Hygiene, Vol. 97, No. 4, 1994, p. 228-230.

Research output: Contribution to journalArticle

Watts, DM, El-Tigani, A, Botros, BAM, Salib, AW, Olson, JG, McCarthy, M & Ksiazek, T 1994, 'Arthropod-borne viral infections associated with a fever outbreak in the Northern Province of Sudan', Journal of Tropical Medicine and Hygiene, vol. 97, no. 4, pp. 228-230.
Watts DM, El-Tigani A, Botros BAM, Salib AW, Olson JG, McCarthy M et al. Arthropod-borne viral infections associated with a fever outbreak in the Northern Province of Sudan. Journal of Tropical Medicine and Hygiene. 1994;97(4):228-230.
Watts, D. M. ; El-Tigani, A. ; Botros, B. A M ; Salib, A. W. ; Olson, J. G. ; McCarthy, M. ; Ksiazek, Thomas. / Arthropod-borne viral infections associated with a fever outbreak in the Northern Province of Sudan. In: Journal of Tropical Medicine and Hygiene. 1994 ; Vol. 97, No. 4. pp. 228-230.
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