Artificial gravity during bed rest deconditioning

A case report

William H. Paloski, Laurence R. Young, Maneesh Arya, Nathaniel Newby, L. Elisabeth Warren, Adrian D. LeBlanc, Scott M. Smith, Sara Zwart, Vincent J. Caiozzo, Kenneth M. Baldwin, Stuart M C Lee, Janice V. Meek, Thomas Jarchow, Kimberly Seaton, Walter Sipes, Brian Crucian, Clarence Sams, Alan Natapoff, Alan H. Feiveson, Satish K. Mehta & 3 others Duane L. Pierson, Raymond Stowe, Maria Hughes

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Artificial gravity (AG) using intermittent short-radius centrifugation has been proposed as a multi-system countermeasure that can protect space travelers from adverse physiological changes associated with microgravity or hypogravity environments. We have recently initiated a ground-based study to investigate the effects of AG on deconditioned subjects, and here we present the findings from our first treatment subject. A 27-year-old male subject was subjected to 21 days of continuous 6° head down tilt bed rest punctuated by daily One-hour spins on a short radius centrifuge providing inertial mechanical loading of 2.5 g at the feet decreasing to 1.0 g at the heart. Functional and mechanistic assessments of bone, muscle, cardiovascular, sensory-motor, immune, and neurocognitive system performance were conducted before, during, and after the bed rest period. Our results indicate that daily centrifugation was effective in reducing the expected negative changes in the bone, muscle, and cardiovascular systems primarily targeted by the countermeasure, and show no negative impacts on the sensory-motor, neurocognitive, or immune systems. Indeed, no adverse effects were observed to be associated with the daily centrifugation. These initial results from one subject are encouraging to the potential efficacy of this countermeasure in reducing the negative physiological effects associated with space travel.

Original languageEnglish (US)
Title of host publicationAIAA 57th International Astronautical Congress, IAC 2006
Pages142-147
Number of pages6
Volume1
StatePublished - 2006
EventAIAA 57th International Astronautical Congress, IAC 2006 - Valencia, Spain
Duration: Oct 2 2006Oct 6 2006

Other

OtherAIAA 57th International Astronautical Congress, IAC 2006
CountrySpain
CityValencia
Period10/2/0610/6/06

Fingerprint

deconditioning
bed rest
artificial gravity
countermeasures
Centrifugation
efferent nervous systems
immune systems
Gravitation
gravity
muscles
microgravity
bones
head down tilt
Muscle
bone
Bone
muscle
physiological effects
cardiovascular system
Cardiovascular system

ASJC Scopus subject areas

  • Space and Planetary Science
  • Aerospace Engineering

Cite this

Paloski, W. H., Young, L. R., Arya, M., Newby, N., Warren, L. E., LeBlanc, A. D., ... Hughes, M. (2006). Artificial gravity during bed rest deconditioning: A case report. In AIAA 57th International Astronautical Congress, IAC 2006 (Vol. 1, pp. 142-147)

Artificial gravity during bed rest deconditioning : A case report. / Paloski, William H.; Young, Laurence R.; Arya, Maneesh; Newby, Nathaniel; Warren, L. Elisabeth; LeBlanc, Adrian D.; Smith, Scott M.; Zwart, Sara; Caiozzo, Vincent J.; Baldwin, Kenneth M.; Lee, Stuart M C; Meek, Janice V.; Jarchow, Thomas; Seaton, Kimberly; Sipes, Walter; Crucian, Brian; Sams, Clarence; Natapoff, Alan; Feiveson, Alan H.; Mehta, Satish K.; Pierson, Duane L.; Stowe, Raymond; Hughes, Maria.

AIAA 57th International Astronautical Congress, IAC 2006. Vol. 1 2006. p. 142-147.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Paloski, WH, Young, LR, Arya, M, Newby, N, Warren, LE, LeBlanc, AD, Smith, SM, Zwart, S, Caiozzo, VJ, Baldwin, KM, Lee, SMC, Meek, JV, Jarchow, T, Seaton, K, Sipes, W, Crucian, B, Sams, C, Natapoff, A, Feiveson, AH, Mehta, SK, Pierson, DL, Stowe, R & Hughes, M 2006, Artificial gravity during bed rest deconditioning: A case report. in AIAA 57th International Astronautical Congress, IAC 2006. vol. 1, pp. 142-147, AIAA 57th International Astronautical Congress, IAC 2006, Valencia, Spain, 10/2/06.
Paloski WH, Young LR, Arya M, Newby N, Warren LE, LeBlanc AD et al. Artificial gravity during bed rest deconditioning: A case report. In AIAA 57th International Astronautical Congress, IAC 2006. Vol. 1. 2006. p. 142-147
Paloski, William H. ; Young, Laurence R. ; Arya, Maneesh ; Newby, Nathaniel ; Warren, L. Elisabeth ; LeBlanc, Adrian D. ; Smith, Scott M. ; Zwart, Sara ; Caiozzo, Vincent J. ; Baldwin, Kenneth M. ; Lee, Stuart M C ; Meek, Janice V. ; Jarchow, Thomas ; Seaton, Kimberly ; Sipes, Walter ; Crucian, Brian ; Sams, Clarence ; Natapoff, Alan ; Feiveson, Alan H. ; Mehta, Satish K. ; Pierson, Duane L. ; Stowe, Raymond ; Hughes, Maria. / Artificial gravity during bed rest deconditioning : A case report. AIAA 57th International Astronautical Congress, IAC 2006. Vol. 1 2006. pp. 142-147
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