Assessment of occupational risk for hantavirus infection in Arizona and New Mexico

Paul S. Zeitz, Judith M. Graber, Ronald A. Voorhees, Clare Kioski, Lee A. Shands, Thomas Ksiazek, Steven Jenison, Rima F. Khabbaz

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Differentiating occupational exposure from other potential domestic or recreational exposure(s) for Sin Nombre virus (SNV) infection is an epidemiologic challenge. Interviews on work-related activities were conducted, and serum specimens were obtained from 494 workers in Arizona and New Mexico. These workers may have been exposed to rodents and rodent excreta at work, but their primary occupation did not require rodent contact (National Park Service [n = 193]; Navajo Agricultural Product Industry [n = 65], utility companies [n = 169] and plumbing and heating contractors [n = 67]). Within each occupational group (farm workers [n = 57], laborers [n = 20], professionals [n = 70], repairs [n = 211], service industry workers [n =83], and technicians [n = 53]), the majority of workers reported working in areas that had rodent droppings (range, 75 to 95%); 70% of laborers and 64% of service industry workers, reported handling rodents. More than 60% of workers in each group, except technicians, reported reopening and cleaning or working in closed spaces. Approximately 90% of laborers, repairers, and farm workers reported hand-plowing. Although the risk for occupationally related SNV infection appears to be low, workers frequently performed risk activities associated with hantavirus pulmonary syndrome (HPS). All workers were seronegative for SNV by enzyme-linked immunoassay or Western blot testing. These findings, the known occupational exposure of some HPS cases, and the high HPS case-fatality rate (52%) support the need for recommendations to reduce human contact with rodents in the workplace. Increased understanding of hantavirus transmission to human will help focus future recommendations to minimize human exposures effectively.

Original languageEnglish (US)
Pages (from-to)463-467
Number of pages5
JournalJournal of Occupational and Environmental Medicine
Volume39
Issue number5
DOIs
StatePublished - May 1997
Externally publishedYes

Fingerprint

Hantavirus Infections
Rodentia
Sin Nombre virus
Hantavirus Pulmonary Syndrome
Industry
Virus Diseases
Occupational Exposure
Sanitary Engineering
Hantavirus
Occupational Groups
Immunoenzyme Techniques
Occupations
Workplace
Heating
Hand
Western Blotting
Interviews
Mortality
Serum

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

Cite this

Assessment of occupational risk for hantavirus infection in Arizona and New Mexico. / Zeitz, Paul S.; Graber, Judith M.; Voorhees, Ronald A.; Kioski, Clare; Shands, Lee A.; Ksiazek, Thomas; Jenison, Steven; Khabbaz, Rima F.

In: Journal of Occupational and Environmental Medicine, Vol. 39, No. 5, 05.1997, p. 463-467.

Research output: Contribution to journalArticle

Zeitz, Paul S. ; Graber, Judith M. ; Voorhees, Ronald A. ; Kioski, Clare ; Shands, Lee A. ; Ksiazek, Thomas ; Jenison, Steven ; Khabbaz, Rima F. / Assessment of occupational risk for hantavirus infection in Arizona and New Mexico. In: Journal of Occupational and Environmental Medicine. 1997 ; Vol. 39, No. 5. pp. 463-467.
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