Assessment of the risk of Ebola virus transmission from bodily fluids and fomites

Daniel G. Bausch, Jonathan S. Towner, Scott F. Dowell, Felix Kaducu, Matthew Lukwiya, Anthony Sanchez, Stuart T. Nichol, Thomas Ksiazek, Pierre E. Rollin

Research output: Contribution to journalArticle

308 Citations (Scopus)

Abstract

Although Ebola virus (EBOV) is transmitted by unprotected physical contact with infected persons, few data exist on which specific bodily fluids are infected or on the risk of fomite transmission. Therefore, we tested various clinical specimens from 26 laboratory-confirmed cases of Ebola hemorrhagic fever, as well as environmental specimens collected from an isolation ward, for the presence of EBOV. Virus was detected by culture and/or reverse-transcription polymerase chain reaction in 16 of 54 clinical specimens (including saliva, stool, semen, breast milk, tears, nasal blood, and a skin swab) and in 2 of 33 environmental specimens.We conclude that EBOV is shed in a wide variety of bodily fluids during the acute period of illness but that the risk of transmission from fomites in an isolation ward and from convalescent patients is low when currently recommended infection control guidelines for the viral hemorrhagic fevers are followed.

Original languageEnglish (US)
JournalJournal of Infectious Diseases
Volume196
Issue numberSUPPL. 2
DOIs
StatePublished - Nov 15 2007
Externally publishedYes

Fingerprint

Fomites
Ebolavirus
Ebola Hemorrhagic Fever
Viral Hemorrhagic Fevers
Human Milk
Infection Control
Semen
Tears
Nose
Saliva
Reverse Transcription
Guidelines
Viruses
Polymerase Chain Reaction
Skin

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Immunology

Cite this

Bausch, D. G., Towner, J. S., Dowell, S. F., Kaducu, F., Lukwiya, M., Sanchez, A., ... Rollin, P. E. (2007). Assessment of the risk of Ebola virus transmission from bodily fluids and fomites. Journal of Infectious Diseases, 196(SUPPL. 2). https://doi.org/10.1086/520545

Assessment of the risk of Ebola virus transmission from bodily fluids and fomites. / Bausch, Daniel G.; Towner, Jonathan S.; Dowell, Scott F.; Kaducu, Felix; Lukwiya, Matthew; Sanchez, Anthony; Nichol, Stuart T.; Ksiazek, Thomas; Rollin, Pierre E.

In: Journal of Infectious Diseases, Vol. 196, No. SUPPL. 2, 15.11.2007.

Research output: Contribution to journalArticle

Bausch, DG, Towner, JS, Dowell, SF, Kaducu, F, Lukwiya, M, Sanchez, A, Nichol, ST, Ksiazek, T & Rollin, PE 2007, 'Assessment of the risk of Ebola virus transmission from bodily fluids and fomites', Journal of Infectious Diseases, vol. 196, no. SUPPL. 2. https://doi.org/10.1086/520545
Bausch DG, Towner JS, Dowell SF, Kaducu F, Lukwiya M, Sanchez A et al. Assessment of the risk of Ebola virus transmission from bodily fluids and fomites. Journal of Infectious Diseases. 2007 Nov 15;196(SUPPL. 2). https://doi.org/10.1086/520545
Bausch, Daniel G. ; Towner, Jonathan S. ; Dowell, Scott F. ; Kaducu, Felix ; Lukwiya, Matthew ; Sanchez, Anthony ; Nichol, Stuart T. ; Ksiazek, Thomas ; Rollin, Pierre E. / Assessment of the risk of Ebola virus transmission from bodily fluids and fomites. In: Journal of Infectious Diseases. 2007 ; Vol. 196, No. SUPPL. 2.
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