Association between changes in Membership and Professional Standards Committee review criteria and use of higher-risk kidneys for transplant

Andrew Wey, Nicholas Salkowski, Robert J. Carrico, Sharon Shepherd, Bertram L. Kasiske, Bryn Thompson, Ajay K. Israni, Jon J. Snyder

Research output: Contribution to journalArticlepeer-review

Abstract

The Organ Procurement and Transplantation Network's Membership and Professional Standards Committee implemented an operational rule on March 1, 2017, intended to increase the number of kidneys transplanted from donors with kidney donor profile index (KDPI) ≥ 85% into recipients with poor estimated posttransplant survival (≥ 80%). Using data from the Scientific Registry of Transplant Recipients, ordinal and logistic regressions estimated, respectively, differences in kidney yield (number of transplanted kidneys per recovered donor) and offer acceptance practices before and after implementation. We included donors recovered January 1, 2016-February 28, 2018. The odds of higher kidney yield for donors with KDPI ≥ 85% were 27% higher after implementation (odds ratio, 1.061.271.53), but odds were also 20% higher for donors with KDPI < 85% (1.041.201.38). Thus, kidney yield was higher for all donors, with a slightly larger difference for donors with KDPI ≥ 85%. Additionally, the difference in offer acceptance before and after implementation was similar regardless of KDPI (KDPI < 85%, 0.971.021.07; KDPI ≥ 85%, 0.951.041.14). In the first year after implementation, kidney yield increased for donors with KDPI < and ≥ 85%. Thus, kidney yield from higher KDPI donors may have increased without the operational rule.

Original languageEnglish (US)
Article numbere13872
JournalClinical Transplantation
Volume34
Issue number7
DOIs
StatePublished - Jul 1 2020
Externally publishedYes

Keywords

  • kidney transplantation
  • kidney yield
  • Membership and Professional Standards Committee
  • offer acceptance
  • Organ Procurement and Transplantation Network
  • regulatory review

ASJC Scopus subject areas

  • Transplantation

Fingerprint

Dive into the research topics of 'Association between changes in Membership and Professional Standards Committee review criteria and use of higher-risk kidneys for transplant'. Together they form a unique fingerprint.

Cite this