Association of a Sindbis-like virus with Ockelbo disease in Sweden

B. Niklasson; A. Espmark; J. W. LeDuc; T. P. Gargan; W. A. Ennis; R. B. Tesh; A. J. Main

doi:10.4269/ajtmh.1984.33.1212

Association of a Sindbis-like virus with Ockelbo disease in Sweden

B. Niklasson, A. Espmark, J. W. LeDuc, T. P. Gargan, W. A. Ennis, R. B. Tesh, A. J. Main

Research output: Contribution to journal › Article › peer-review

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Abstract

An alphavirus isolated from Culiseta mosquitoes has been associated with Ockelbo disease, an exanthema arthralgia syndrome occurring in Sweden. The isolate was made from mosquitoes collected in Edsbyn (central Sweden), an area with considerable Ockelbo disease morbidity. This isolate proved to be indistinguishable from Sindbis virus by complement-fixation and hemagglutination-inhibition tests, and was antigenically related to Sindbis in plaque reduction neutralization tests. Patients with Ockelbo disease developed neutralizing antibodies to the virus in their convalescent sera, suggesting that it is the etiologic agent of the disease.

Original language	English (US)
Pages (from-to)	1212-1217
Number of pages	6
Journal	American Journal of Tropical Medicine and Hygiene
Volume	33
Issue number	6
DOIs	https://doi.org/10.4269/ajtmh.1984.33.1212
State	Published - 1984
Externally published	Yes

ASJC Scopus subject areas

Infectious Diseases
Virology
Parasitology

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10.4269/ajtmh.1984.33.1212

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title = "Association of a Sindbis-like virus with Ockelbo disease in Sweden",

abstract = "An alphavirus isolated from Culiseta mosquitoes has been associated with Ockelbo disease, an exanthema arthralgia syndrome occurring in Sweden. The isolate was made from mosquitoes collected in Edsbyn (central Sweden), an area with considerable Ockelbo disease morbidity. This isolate proved to be indistinguishable from Sindbis virus by complement-fixation and hemagglutination-inhibition tests, and was antigenically related to Sindbis in plaque reduction neutralization tests. Patients with Ockelbo disease developed neutralizing antibodies to the virus in their convalescent sera, suggesting that it is the etiologic agent of the disease.",

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T1 - Association of a Sindbis-like virus with Ockelbo disease in Sweden

AU - Niklasson, B.

AU - Espmark, A.

AU - LeDuc, J. W.

AU - Gargan, T. P.

AU - Ennis, W. A.

AU - Tesh, R. B.

AU - Main, A. J.

PY - 1984

Y1 - 1984

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AB - An alphavirus isolated from Culiseta mosquitoes has been associated with Ockelbo disease, an exanthema arthralgia syndrome occurring in Sweden. The isolate was made from mosquitoes collected in Edsbyn (central Sweden), an area with considerable Ockelbo disease morbidity. This isolate proved to be indistinguishable from Sindbis virus by complement-fixation and hemagglutination-inhibition tests, and was antigenically related to Sindbis in plaque reduction neutralization tests. Patients with Ockelbo disease developed neutralizing antibodies to the virus in their convalescent sera, suggesting that it is the etiologic agent of the disease.

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Association of a Sindbis-like virus with Ockelbo disease in Sweden

Abstract

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