Association of a Sindbis-like virus with Ockelbo disease in Sweden

B. Niklasson, A. Espmark, James LeDuc, T. P. Gargan, W. A. Ennis, R. B. Tesh, A. J. Main

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

An alphavirus isolated from Culiseta mosquitoes has been associated with Ockelbo disease, an exanthema arthralgia syndrome occurring in Sweden. The isolate was made from mosquitoes collected in Edsbyn (central Sweden), an area with considerable Ockelbo disease morbidity. This isolate proved to be indistinguishable from Sindbis virus by complement-fixation and hemagglutination-inhibition tests, and was antigenically related to Sindbis in plaque reduction neutralization tests. Patients with Ockelbo disease developed neutralizing antibodies to the virus in their convalescent sera, suggesting that it is the etiologic agent of the disease.

Original languageEnglish (US)
Pages (from-to)1212-1217
Number of pages6
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume33
Issue number6
StatePublished - 1984
Externally publishedYes

Fingerprint

Sindbis Virus
Sweden
Culicidae
Alphavirus
Hemagglutination Inhibition Tests
Neutralization Tests
Arthralgia
Exanthema
Neutralizing Antibodies
Viruses
Morbidity
Serum

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Niklasson, B., Espmark, A., LeDuc, J., Gargan, T. P., Ennis, W. A., Tesh, R. B., & Main, A. J. (1984). Association of a Sindbis-like virus with Ockelbo disease in Sweden. American Journal of Tropical Medicine and Hygiene, 33(6), 1212-1217.

Association of a Sindbis-like virus with Ockelbo disease in Sweden. / Niklasson, B.; Espmark, A.; LeDuc, James; Gargan, T. P.; Ennis, W. A.; Tesh, R. B.; Main, A. J.

In: American Journal of Tropical Medicine and Hygiene, Vol. 33, No. 6, 1984, p. 1212-1217.

Research output: Contribution to journalArticle

Niklasson, B, Espmark, A, LeDuc, J, Gargan, TP, Ennis, WA, Tesh, RB & Main, AJ 1984, 'Association of a Sindbis-like virus with Ockelbo disease in Sweden', American Journal of Tropical Medicine and Hygiene, vol. 33, no. 6, pp. 1212-1217.
Niklasson B, Espmark A, LeDuc J, Gargan TP, Ennis WA, Tesh RB et al. Association of a Sindbis-like virus with Ockelbo disease in Sweden. American Journal of Tropical Medicine and Hygiene. 1984;33(6):1212-1217.
Niklasson, B. ; Espmark, A. ; LeDuc, James ; Gargan, T. P. ; Ennis, W. A. ; Tesh, R. B. ; Main, A. J. / Association of a Sindbis-like virus with Ockelbo disease in Sweden. In: American Journal of Tropical Medicine and Hygiene. 1984 ; Vol. 33, No. 6. pp. 1212-1217.
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