Association of clinical intra-amniotic infection and meconium

T. S. Wen, N. L. Eriksen, J. D. Blanco, J. M. Graham, B. T. Oshiro, J. A. Prieto

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

The objective of this study was to determine the rate of intra-amniotic infection in patients with meconium-stained amniotic fluid compared to controls. With a retrospective case-controlled study design, we compared 100 pregnant women with meconium to 100 pregnant women without meconium for the development of intra-amniotic infection. Patients delivered between September 1 and December 31, 1990. Exclusion criteria were active infection prior to labor or antibiotic use within the 7 days prior to delivery. We diagnosed clinical intra-amniotic infection in patients with ruptured membranes by a maternal temperature 100.4°F or higher and any two of the following: maternal or fetal tachycardia, uterine tenderness, white blood cell count 10,500 mm3 or more, or foul-smelling amniotic fluid. Demographic variables, labor characteristics, maternal infectious morbidity, and neonatal outcome were analyzed using the Wilcoxin rank test, chi-square test, or Fisher's exact test as appropriate. The rate of clinical intra-amniotic infection was significantly higher in women with meconium-stained amniotic fluid (8%) compared with women with no meconium (2%) (p = 0.05).

Original languageEnglish (US)
Pages (from-to)438-440
Number of pages3
JournalAmerican Journal of Perinatology
Volume10
Issue number6
StatePublished - 1993
Externally publishedYes

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Meconium
Amniotic Fluid
Infection
Mothers
Pregnant Women
Chi-Square Distribution
Leukocyte Count
Tachycardia
Demography
Anti-Bacterial Agents
Morbidity
Temperature
Membranes

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Pediatrics, Perinatology, and Child Health

Cite this

Wen, T. S., Eriksen, N. L., Blanco, J. D., Graham, J. M., Oshiro, B. T., & Prieto, J. A. (1993). Association of clinical intra-amniotic infection and meconium. American Journal of Perinatology, 10(6), 438-440.

Association of clinical intra-amniotic infection and meconium. / Wen, T. S.; Eriksen, N. L.; Blanco, J. D.; Graham, J. M.; Oshiro, B. T.; Prieto, J. A.

In: American Journal of Perinatology, Vol. 10, No. 6, 1993, p. 438-440.

Research output: Contribution to journalArticle

Wen, TS, Eriksen, NL, Blanco, JD, Graham, JM, Oshiro, BT & Prieto, JA 1993, 'Association of clinical intra-amniotic infection and meconium', American Journal of Perinatology, vol. 10, no. 6, pp. 438-440.
Wen TS, Eriksen NL, Blanco JD, Graham JM, Oshiro BT, Prieto JA. Association of clinical intra-amniotic infection and meconium. American Journal of Perinatology. 1993;10(6):438-440.
Wen, T. S. ; Eriksen, N. L. ; Blanco, J. D. ; Graham, J. M. ; Oshiro, B. T. ; Prieto, J. A. / Association of clinical intra-amniotic infection and meconium. In: American Journal of Perinatology. 1993 ; Vol. 10, No. 6. pp. 438-440.
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