Association of intraspecific wounding with hantaviral infection in wild rats (Rattus norvegicus)

G. E. Glass, J. E. Childs, G. W. Korch, James LeDuc

Research output: Contribution to journalArticle

153 Citations (Scopus)

Abstract

The potential for hantaviral transmission among wild Norway rats by wounding associated with aggressive interactions was evaluated using a prospective seroepidemiological study coupled with a mark-release-recapture survey. There was a significant association between an animal's serological status and the presence of wounds. Longitudinal studies of marked and released animals showed seroconversion between captures was associated with wounding between captures more often (33%) than expected by chance, while unwounded animals seroconverted less often (8%) than expected. Typically, less than a 5% difference was found when comparing the incidence of seroconversion with the predicted rate based on wounding and seroprevalence. Infection was highly associated with the onset of sexual maturity and aggression but decoupled from rat age and the length of environmental exposure. Seroconversions occurred at times most associated with aggressive encounters and least associated with amicable behaviours that could lead to aerosol transmission.

Original languageEnglish (US)
Pages (from-to)459-472
Number of pages14
JournalEpidemiology and Infection
Volume101
Issue number2
StatePublished - 1988
Externally publishedYes

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Seroepidemiologic Studies
Infection
Environmental Exposure
Aerosols
Aggression
Longitudinal Studies
Prospective Studies
Incidence
Wounds and Injuries
Seroconversion
Surveys and Questionnaires

ASJC Scopus subject areas

  • Immunology
  • Public Health, Environmental and Occupational Health

Cite this

Association of intraspecific wounding with hantaviral infection in wild rats (Rattus norvegicus). / Glass, G. E.; Childs, J. E.; Korch, G. W.; LeDuc, James.

In: Epidemiology and Infection, Vol. 101, No. 2, 1988, p. 459-472.

Research output: Contribution to journalArticle

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