Attack behaviour in mice inhibited by Δ-9-Tetrahydrocannabinol

M. Marlyne Kilbey, G. Edward Fritchie, David M. Mclendon, Kenneth M. Johnson

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

MARIJUANA and its active major ingredient, Δ-9-tetrahydrocan-nabinol (THC), reduce fighting among previously isolated mice1 and decrease preference for the side of a T-maze where they are rewarded by the opportunity to attack2. The degree of suppression of fighting behaviour seemed to be related to the cannabis resin content of the extract administered 1. The behavioural effects which we reported2 could not be assessed for a THC dose-dependent relationship as some mice in the low-dosage group received faulty intravenous injections.

Original languageEnglish (US)
Pages (from-to)463-465
Number of pages3
JournalNature
Volume238
Issue number5365
DOIs
StatePublished - Dec 1 1972

ASJC Scopus subject areas

  • General

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