Atypical ductal hyperplasia of the breast diagnosed by 11-gauge directional vacuum-assisted biopsy

Arvin Rao, Steve Parker, Erick Ratzer, Janet Stephens, Michael Fenoglio, Vicki Klimberg, Walter Biffl

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Background: Small nonpalpable mammographic abnormalities are frequently diagnosed by percutaneous stereotactically guided core needle biopsy. The reliability of the histologic diagnosis of atypical ductal hyperplasia (ADH) made from tissue obtained by 11-gauge directional, vacuum-assisted biopsy of these nonpalpable breast lesions is unknown. Methods: The records of 31 patients who were found to have ADH by 11-gauge directional vacuum-assisted biopsy were reviewed. All of these patients subsequently underwent surgical excision with needle localization biopsy of the ADH and they are the subjects of this retrospective study. Results: Eleven of the 31 patients with ADH on 11-gauge directional vacuum-assisted biopsy were upgraded to ductal carcinoma in situ or infiltrating carcinoma by the excisional biopsy. This was a 35% underestimation of malignancy in our patients. Conclusions: When the histologic diagnosis of ADH is made from tissue harvested by an 11-gauge directional vacuum assisted biopsy, surgical excision of the entire abnormality is recommended to avoid underdiagnosis of breast cancer.

Original languageEnglish (US)
Pages (from-to)534-537
Number of pages4
JournalAmerican Journal of Surgery
Volume184
Issue number6
DOIs
StatePublished - Dec 1 2002
Externally publishedYes

Fingerprint

Carcinoma, Intraductal, Noninfiltrating
Vacuum
Breast
Biopsy
Large-Core Needle Biopsy
Needle Biopsy
Retrospective Studies
Breast Neoplasms
Carcinoma
Neoplasms

Keywords

  • 11-Gauge needle biopsy
  • Atypical ductal hyperplasia
  • Excisional biopsy

ASJC Scopus subject areas

  • Surgery

Cite this

Atypical ductal hyperplasia of the breast diagnosed by 11-gauge directional vacuum-assisted biopsy. / Rao, Arvin; Parker, Steve; Ratzer, Erick; Stephens, Janet; Fenoglio, Michael; Klimberg, Vicki; Biffl, Walter.

In: American Journal of Surgery, Vol. 184, No. 6, 01.12.2002, p. 534-537.

Research output: Contribution to journalArticle

Rao, Arvin ; Parker, Steve ; Ratzer, Erick ; Stephens, Janet ; Fenoglio, Michael ; Klimberg, Vicki ; Biffl, Walter. / Atypical ductal hyperplasia of the breast diagnosed by 11-gauge directional vacuum-assisted biopsy. In: American Journal of Surgery. 2002 ; Vol. 184, No. 6. pp. 534-537.
@article{d140a68a19a7496ba189c7286589b691,
title = "Atypical ductal hyperplasia of the breast diagnosed by 11-gauge directional vacuum-assisted biopsy",
abstract = "Background: Small nonpalpable mammographic abnormalities are frequently diagnosed by percutaneous stereotactically guided core needle biopsy. The reliability of the histologic diagnosis of atypical ductal hyperplasia (ADH) made from tissue obtained by 11-gauge directional, vacuum-assisted biopsy of these nonpalpable breast lesions is unknown. Methods: The records of 31 patients who were found to have ADH by 11-gauge directional vacuum-assisted biopsy were reviewed. All of these patients subsequently underwent surgical excision with needle localization biopsy of the ADH and they are the subjects of this retrospective study. Results: Eleven of the 31 patients with ADH on 11-gauge directional vacuum-assisted biopsy were upgraded to ductal carcinoma in situ or infiltrating carcinoma by the excisional biopsy. This was a 35{\%} underestimation of malignancy in our patients. Conclusions: When the histologic diagnosis of ADH is made from tissue harvested by an 11-gauge directional vacuum assisted biopsy, surgical excision of the entire abnormality is recommended to avoid underdiagnosis of breast cancer.",
keywords = "11-Gauge needle biopsy, Atypical ductal hyperplasia, Excisional biopsy",
author = "Arvin Rao and Steve Parker and Erick Ratzer and Janet Stephens and Michael Fenoglio and Vicki Klimberg and Walter Biffl",
year = "2002",
month = "12",
day = "1",
doi = "10.1016/S0002-9610(02)01107-8",
language = "English (US)",
volume = "184",
pages = "534--537",
journal = "American Journal of Surgery",
issn = "0002-9610",
publisher = "Elsevier Inc.",
number = "6",

}

TY - JOUR

T1 - Atypical ductal hyperplasia of the breast diagnosed by 11-gauge directional vacuum-assisted biopsy

AU - Rao, Arvin

AU - Parker, Steve

AU - Ratzer, Erick

AU - Stephens, Janet

AU - Fenoglio, Michael

AU - Klimberg, Vicki

AU - Biffl, Walter

PY - 2002/12/1

Y1 - 2002/12/1

N2 - Background: Small nonpalpable mammographic abnormalities are frequently diagnosed by percutaneous stereotactically guided core needle biopsy. The reliability of the histologic diagnosis of atypical ductal hyperplasia (ADH) made from tissue obtained by 11-gauge directional, vacuum-assisted biopsy of these nonpalpable breast lesions is unknown. Methods: The records of 31 patients who were found to have ADH by 11-gauge directional vacuum-assisted biopsy were reviewed. All of these patients subsequently underwent surgical excision with needle localization biopsy of the ADH and they are the subjects of this retrospective study. Results: Eleven of the 31 patients with ADH on 11-gauge directional vacuum-assisted biopsy were upgraded to ductal carcinoma in situ or infiltrating carcinoma by the excisional biopsy. This was a 35% underestimation of malignancy in our patients. Conclusions: When the histologic diagnosis of ADH is made from tissue harvested by an 11-gauge directional vacuum assisted biopsy, surgical excision of the entire abnormality is recommended to avoid underdiagnosis of breast cancer.

AB - Background: Small nonpalpable mammographic abnormalities are frequently diagnosed by percutaneous stereotactically guided core needle biopsy. The reliability of the histologic diagnosis of atypical ductal hyperplasia (ADH) made from tissue obtained by 11-gauge directional, vacuum-assisted biopsy of these nonpalpable breast lesions is unknown. Methods: The records of 31 patients who were found to have ADH by 11-gauge directional vacuum-assisted biopsy were reviewed. All of these patients subsequently underwent surgical excision with needle localization biopsy of the ADH and they are the subjects of this retrospective study. Results: Eleven of the 31 patients with ADH on 11-gauge directional vacuum-assisted biopsy were upgraded to ductal carcinoma in situ or infiltrating carcinoma by the excisional biopsy. This was a 35% underestimation of malignancy in our patients. Conclusions: When the histologic diagnosis of ADH is made from tissue harvested by an 11-gauge directional vacuum assisted biopsy, surgical excision of the entire abnormality is recommended to avoid underdiagnosis of breast cancer.

KW - 11-Gauge needle biopsy

KW - Atypical ductal hyperplasia

KW - Excisional biopsy

UR - http://www.scopus.com/inward/record.url?scp=0036911027&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036911027&partnerID=8YFLogxK

U2 - 10.1016/S0002-9610(02)01107-8

DO - 10.1016/S0002-9610(02)01107-8

M3 - Article

VL - 184

SP - 534

EP - 537

JO - American Journal of Surgery

JF - American Journal of Surgery

SN - 0002-9610

IS - 6

ER -