Atypical ductal hyperplasia of the breast diagnosed by 11-gauge directional vacuum-assisted biopsy

Arvin Rao, Steve Parker, Erick Ratzer, Janet Stephens, Michael Fenoglio, Vicki Klimberg, Walter Biffl

Research output: Contribution to journalArticle

42 Scopus citations

Abstract

Background: Small nonpalpable mammographic abnormalities are frequently diagnosed by percutaneous stereotactically guided core needle biopsy. The reliability of the histologic diagnosis of atypical ductal hyperplasia (ADH) made from tissue obtained by 11-gauge directional, vacuum-assisted biopsy of these nonpalpable breast lesions is unknown. Methods: The records of 31 patients who were found to have ADH by 11-gauge directional vacuum-assisted biopsy were reviewed. All of these patients subsequently underwent surgical excision with needle localization biopsy of the ADH and they are the subjects of this retrospective study. Results: Eleven of the 31 patients with ADH on 11-gauge directional vacuum-assisted biopsy were upgraded to ductal carcinoma in situ or infiltrating carcinoma by the excisional biopsy. This was a 35% underestimation of malignancy in our patients. Conclusions: When the histologic diagnosis of ADH is made from tissue harvested by an 11-gauge directional vacuum assisted biopsy, surgical excision of the entire abnormality is recommended to avoid underdiagnosis of breast cancer.

Original languageEnglish (US)
Pages (from-to)534-537
Number of pages4
JournalAmerican Journal of Surgery
Volume184
Issue number6
DOIs
StatePublished - Dec 1 2002
Externally publishedYes

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Keywords

  • 11-Gauge needle biopsy
  • Atypical ductal hyperplasia
  • Excisional biopsy

ASJC Scopus subject areas

  • Surgery

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