Atypical Systemic Neonatal Herpes Diagnosed Incidentally in Twin Infants

Diana Kim Nguyen, Diana Cabrera Fernandez, John I. Coon, Janak Patel

Research output: Contribution to journalArticlepeer-review


Neonatal herpes simplex virus (HSV) infections are serious infections that usually occur in the first few weeks of life. Infants generally present with mucocutaneous lesions, central nervous system infection, and/or systemic disease. In this case report, we describe a set of twins that had unexpected presentations of neonatal HSV. Twin A was diagnosed incidentally on routine eye exam, and Twin B was diagnosed only because his twin was found to be infected; both infants were still hospitalized and were beyond 1 month of age. These twins exhibited atypical manifestations that diverge from the 3 main categories of neonatal HSV and expand our understanding of the spectrum of disease.

Original languageEnglish (US)
Article numbere2022058887
Issue number1
StatePublished - Jul 1 2023
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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