TY - JOUR
T1 - Autoimmune Thyroid Encephalopathy Presenting with Epilepsia Partialis Continua
AU - Aydin-Özemir, Zeynep
AU - Tüzün, Erdem
AU - Baykan, Betül
AU - Akman-Demir, Gülşen
AU - Özbey, Neşe
AU - Gürses, Candan
AU - Christadoss, Premkumar
AU - Gökyiğit, Ayşen
PY - 2006/7
Y1 - 2006/7
N2 - We report the first case of an autoimmune thyroid encephalopathy presenting with multifocal motor status epilepticus. A 37-year-old female patient was admitted with multifocal motor seizures intractable to intravenous status epilepticus treatments, asymmetrical quadriparesis, truncal ataxia and continuous semi-rhythmical jerks. Pathological signal alterations were detected in both precentral cortices in MRI examination. Autoimmune thyroiditis was diagnosed after radiological examinations of the thyroid gland and thyroid function tests. Seizures promptly ceased following intravenous steroid treatment. Immunohistochemistry studies showed mild to moderate neuronal staining with the plasma and CSF samples. Remarkably, autoimmune thyroiditis may present with migrating focal motor status epilepticus. We recommend anti-thyroid antibody screening for multifocal motor status epilepticus cases of unspecified cause.
AB - We report the first case of an autoimmune thyroid encephalopathy presenting with multifocal motor status epilepticus. A 37-year-old female patient was admitted with multifocal motor seizures intractable to intravenous status epilepticus treatments, asymmetrical quadriparesis, truncal ataxia and continuous semi-rhythmical jerks. Pathological signal alterations were detected in both precentral cortices in MRI examination. Autoimmune thyroiditis was diagnosed after radiological examinations of the thyroid gland and thyroid function tests. Seizures promptly ceased following intravenous steroid treatment. Immunohistochemistry studies showed mild to moderate neuronal staining with the plasma and CSF samples. Remarkably, autoimmune thyroiditis may present with migrating focal motor status epilepticus. We recommend anti-thyroid antibody screening for multifocal motor status epilepticus cases of unspecified cause.
KW - Hashimoto's Disease
KW - Status Epilepticus
KW - Thyroid Encephalopathy
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U2 - 10.1177/155005940603700308
DO - 10.1177/155005940603700308
M3 - Article
C2 - 16929705
AN - SCOPUS:33747128922
SN - 1550-0594
VL - 37
SP - 204
EP - 209
JO - Clinical EEG and Neuroscience
JF - Clinical EEG and Neuroscience
IS - 3
ER -