Avian and human metapneumovirus

Shobha Broor, Preeti Bharaj

Research output: Chapter in Book/Report/Conference proceedingConference contribution

14 Scopus citations

Abstract

Pneumovirus infection remains a significant problem for both human and veterinary medicine. Both avian pneumovirus (aMPV, Turkey rhinotracheitis virus) and human metapneumovirus (hMPV) are pathogens of birds and humans, which are associated with respiratory tract infections. Based on their different genomic organization and low level of nucleotide (nt) and amino acid (aa) identity with paramyxoviruses in the genus Pneumovirus, aMPV and hMPV have been classified into a new genus referred to as Metapneumovirus. The advancement of our understanding of pneumovirus biology and pathogenesis of pneumovirus disease in specific natural hosts can provide us with strategies for vaccine formulations and combined antiviral and immunomodulatory therapies.

Original languageEnglish (US)
Title of host publicationAnnals of the New York Academy of Sciences
Pages66-85
Number of pages20
Volume1102
DOIs
StatePublished - Apr 2007
Externally publishedYes

Publication series

NameAnnals of the New York Academy of Sciences
Volume1102
ISSN (Print)00778923
ISSN (Electronic)17496632

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Keywords

  • Avian pneumovirus
  • Human metapneumovirus
  • Nucleotide
  • Pathogenesis
  • Sequence identity

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Broor, S., & Bharaj, P. (2007). Avian and human metapneumovirus. In Annals of the New York Academy of Sciences (Vol. 1102, pp. 66-85). (Annals of the New York Academy of Sciences; Vol. 1102). https://doi.org/10.1196/annals.1408.005