Avian and human metapneumovirus

Shobha Broor, Preeti Bharaj

Research output: Chapter in Book/Report/Conference proceedingConference contribution

15 Scopus citations

Abstract

Pneumovirus infection remains a significant problem for both human and veterinary medicine. Both avian pneumovirus (aMPV, Turkey rhinotracheitis virus) and human metapneumovirus (hMPV) are pathogens of birds and humans, which are associated with respiratory tract infections. Based on their different genomic organization and low level of nucleotide (nt) and amino acid (aa) identity with paramyxoviruses in the genus Pneumovirus, aMPV and hMPV have been classified into a new genus referred to as Metapneumovirus. The advancement of our understanding of pneumovirus biology and pathogenesis of pneumovirus disease in specific natural hosts can provide us with strategies for vaccine formulations and combined antiviral and immunomodulatory therapies.

Original languageEnglish (US)
Title of host publicationBiology of Emerging Viruses
Subtitle of host publicationSARS, Avian and Human Influenza, Metapneumovirus, Nipah, West Nile, and Ross River Virus
PublisherBlackwell Publishing Inc.
Pages66-85
Number of pages20
ISBN (Print)1573316903, 9781573316903
DOIs
StatePublished - Apr 2007

Publication series

NameAnnals of the New York Academy of Sciences
Volume1102
ISSN (Print)0077-8923
ISSN (Electronic)1749-6632

Keywords

  • Avian pneumovirus
  • Human metapneumovirus
  • Nucleotide
  • Pathogenesis
  • Sequence identity

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

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  • Cite this

    Broor, S., & Bharaj, P. (2007). Avian and human metapneumovirus. In Biology of Emerging Viruses: SARS, Avian and Human Influenza, Metapneumovirus, Nipah, West Nile, and Ross River Virus (pp. 66-85). (Annals of the New York Academy of Sciences; Vol. 1102). Blackwell Publishing Inc.. https://doi.org/10.1196/annals.1408.005