Avian influenza a H5N1 virus

Michael J. Loeffelholz

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Although influenza A viruses of avian origin have long been responsible for influenza pandemics, including the " Spanish flu" pandemic of 1918, human infections caused by avian subtypes of influenza A virus, most notably H5N1, have emerged since the 1990s (H5N1 in 1997; H9N2 in 1999; and H7N7 in 2003). The wide geographic distribution of influenza A H5N1 in avian species, and the number and severity of human infections are unprecedented. Together with the ongoing genetic evolution of this virus, these features make influenza A H5N1 a likely candidate for a future influenza pandemic. This article discusses the epidemiology, pathogenesis, and diagnosis of human infections caused by influenza A H5N1 virus.

Original languageEnglish (US)
Pages (from-to)1-20
Number of pages20
JournalClinics in Laboratory Medicine
Volume30
Issue number1
DOIs
StatePublished - Mar 2010

Fingerprint

H5N1 Subtype Influenza A Virus
Influenza in Birds
Viruses
Human Influenza
Influenza A virus
Pandemics
Infection
Epidemiology
Molecular Evolution

Keywords

  • Avian influenza A H5N1 virus
  • Diagnosis
  • Epidemiology
  • Influenza

ASJC Scopus subject areas

  • Biochemistry, medical
  • Clinical Biochemistry

Cite this

Avian influenza a H5N1 virus. / Loeffelholz, Michael J.

In: Clinics in Laboratory Medicine, Vol. 30, No. 1, 03.2010, p. 1-20.

Research output: Contribution to journalArticle

Loeffelholz, Michael J. / Avian influenza a H5N1 virus. In: Clinics in Laboratory Medicine. 2010 ; Vol. 30, No. 1. pp. 1-20.
@article{912f5eecbbf742f8beca8e7a15f5c951,
title = "Avian influenza a H5N1 virus",
abstract = "Although influenza A viruses of avian origin have long been responsible for influenza pandemics, including the {"} Spanish flu{"} pandemic of 1918, human infections caused by avian subtypes of influenza A virus, most notably H5N1, have emerged since the 1990s (H5N1 in 1997; H9N2 in 1999; and H7N7 in 2003). The wide geographic distribution of influenza A H5N1 in avian species, and the number and severity of human infections are unprecedented. Together with the ongoing genetic evolution of this virus, these features make influenza A H5N1 a likely candidate for a future influenza pandemic. This article discusses the epidemiology, pathogenesis, and diagnosis of human infections caused by influenza A H5N1 virus.",
keywords = "Avian influenza A H5N1 virus, Diagnosis, Epidemiology, Influenza",
author = "Loeffelholz, {Michael J.}",
year = "2010",
month = "3",
doi = "10.1016/j.cll.2009.10.005",
language = "English (US)",
volume = "30",
pages = "1--20",
journal = "Clinics in Laboratory Medicine",
issn = "0272-2712",
publisher = "W.B. Saunders Ltd",
number = "1",

}

TY - JOUR

T1 - Avian influenza a H5N1 virus

AU - Loeffelholz, Michael J.

PY - 2010/3

Y1 - 2010/3

N2 - Although influenza A viruses of avian origin have long been responsible for influenza pandemics, including the " Spanish flu" pandemic of 1918, human infections caused by avian subtypes of influenza A virus, most notably H5N1, have emerged since the 1990s (H5N1 in 1997; H9N2 in 1999; and H7N7 in 2003). The wide geographic distribution of influenza A H5N1 in avian species, and the number and severity of human infections are unprecedented. Together with the ongoing genetic evolution of this virus, these features make influenza A H5N1 a likely candidate for a future influenza pandemic. This article discusses the epidemiology, pathogenesis, and diagnosis of human infections caused by influenza A H5N1 virus.

AB - Although influenza A viruses of avian origin have long been responsible for influenza pandemics, including the " Spanish flu" pandemic of 1918, human infections caused by avian subtypes of influenza A virus, most notably H5N1, have emerged since the 1990s (H5N1 in 1997; H9N2 in 1999; and H7N7 in 2003). The wide geographic distribution of influenza A H5N1 in avian species, and the number and severity of human infections are unprecedented. Together with the ongoing genetic evolution of this virus, these features make influenza A H5N1 a likely candidate for a future influenza pandemic. This article discusses the epidemiology, pathogenesis, and diagnosis of human infections caused by influenza A H5N1 virus.

KW - Avian influenza A H5N1 virus

KW - Diagnosis

KW - Epidemiology

KW - Influenza

UR - http://www.scopus.com/inward/record.url?scp=77953355628&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77953355628&partnerID=8YFLogxK

U2 - 10.1016/j.cll.2009.10.005

DO - 10.1016/j.cll.2009.10.005

M3 - Article

VL - 30

SP - 1

EP - 20

JO - Clinics in Laboratory Medicine

JF - Clinics in Laboratory Medicine

SN - 0272-2712

IS - 1

ER -