Axial resolution of laser optoacoustic imaging

Influence of acoustic attenuation and diffraction

Rinat Esenaliev, Herve Alma, Frank K. Tittel, Alexander A. Oraevsky

Research output: Chapter in Book/Report/Conference proceedingConference contribution

13 Citations (Scopus)

Abstract

Laser optoacoustic imaging can be applied for characterization of layered and heterogeneous tissue structures in vivo. Accurate tissue characterization may provide: (1) means for medical diagnoses, and (2) pretreatment tissue properties important for therapeutic laser procedures. Axial resolution of the optoacoustic imaging is higher than that of optical imaging. However, the resolution may degrade due to either attenuation of high-frequency ultrasonic waves in tissue, or/and diffraction of low-frequency acoustic waves. The goal of this study was to determine the axial resolution as a function of acoustic attenuation and diffraction upon propagation of laser-induced pressure waves in water with absorbing layer, in breast phantoms, and in biological tissues. Acoustic pressure measurements were performed in absolute values using piezoelectric transducers. A layer or a small sphere of absorbing medium was placed within a medium with lower optical absorption. The distance between the acoustic transducer and the absorbing object was varied, so that the effects of acoustic attenuation and diffraction could be observed. The location of layers or spheres was measured from recorded optoacoustic pressure profiles and compared with real values measured with a micrometer. The experimental results were analyzed using theoretical models for spherical and planar acoustic waves. Our studies demonstrated that despite strong acoustic attenuation of high-frequency ultrasonic waves, the axial resolution of laser optoacoustic imaging may be as high as 20 μm for tissue layers located at a 5-mm depth. An axial resolution of 10 μm to 20 μm was demonstrated for an absorbing layer at a distance of 5 cm in water, when the resolution is affected only by diffraction. Acoustic transducers employed in optoacoustic imaging can have either high sensitivity or fast temporal response. Therefore, a high resolution may not be achieved with sensitive transducers utilized in breast imaging. For the laser optoacoustic imaging in breast phantoms, the axial resolution was better than 0.5 mm.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsS.L. Jacques
Pages294-306
Number of pages13
Volume3254
DOIs
StatePublished - 1998
EventLaser-Tissue Interaction IX - San Jose, CA, United States
Duration: Jan 26 1998Jan 28 1998

Other

OtherLaser-Tissue Interaction IX
CountryUnited States
CitySan Jose, CA
Period1/26/981/28/98

Fingerprint

acoustic attenuation
Photoacoustic effect
Diffraction
Acoustics
Imaging techniques
Tissue
Lasers
diffraction
lasers
acoustics
breast
Acoustic transducers
transducers
Ultrasonic waves
ultrasonic radiation
diffraction propagation
Acoustic waves
Piezoelectric transducers
piezoelectric transducers
pressure measurement

Keywords

  • Acoustic transducer
  • Cancer detection
  • Laser ultrasound
  • Thermal stress
  • Tissue characterization

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Esenaliev, R., Alma, H., Tittel, F. K., & Oraevsky, A. A. (1998). Axial resolution of laser optoacoustic imaging: Influence of acoustic attenuation and diffraction. In S. L. Jacques (Ed.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 3254, pp. 294-306) https://doi.org/10.1117/12.308176

Axial resolution of laser optoacoustic imaging : Influence of acoustic attenuation and diffraction. / Esenaliev, Rinat; Alma, Herve; Tittel, Frank K.; Oraevsky, Alexander A.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / S.L. Jacques. Vol. 3254 1998. p. 294-306.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Esenaliev, R, Alma, H, Tittel, FK & Oraevsky, AA 1998, Axial resolution of laser optoacoustic imaging: Influence of acoustic attenuation and diffraction. in SL Jacques (ed.), Proceedings of SPIE - The International Society for Optical Engineering. vol. 3254, pp. 294-306, Laser-Tissue Interaction IX, San Jose, CA, United States, 1/26/98. https://doi.org/10.1117/12.308176
Esenaliev R, Alma H, Tittel FK, Oraevsky AA. Axial resolution of laser optoacoustic imaging: Influence of acoustic attenuation and diffraction. In Jacques SL, editor, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3254. 1998. p. 294-306 https://doi.org/10.1117/12.308176
Esenaliev, Rinat ; Alma, Herve ; Tittel, Frank K. ; Oraevsky, Alexander A. / Axial resolution of laser optoacoustic imaging : Influence of acoustic attenuation and diffraction. Proceedings of SPIE - The International Society for Optical Engineering. editor / S.L. Jacques. Vol. 3254 1998. pp. 294-306
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