B to A transition of DNA on the nanosecond time scale

Liqiu Yang, Bernard Pettitt

Research output: Contribution to journalArticle

87 Citations (Scopus)

Abstract

A 3.5-ns atomic-level computer simulation of a DNA solution was performed. We found that a dodecamer of DNA, which contains the recognition site for Eco RI endonuclease, transforms from B-form to A-form in 0.45 M salt water. This supports an earlier proposal on the A-DNA binding site for transcription factor III.

Original languageEnglish (US)
Pages (from-to)2564-2566
Number of pages3
JournalJournal of Physical Chemistry
Volume100
Issue number7
StatePublished - Feb 15 1996
Externally publishedYes

Fingerprint

DNA
A-Form DNA
deoxyribonucleic acid
Deoxyribonuclease EcoRI
Saline water
Endonucleases
Transcription factors
Transcription Factors
Binding Sites
Binding sites
proposals
Computer simulation
computerized simulation
salts
water

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry

Cite this

B to A transition of DNA on the nanosecond time scale. / Yang, Liqiu; Pettitt, Bernard.

In: Journal of Physical Chemistry, Vol. 100, No. 7, 15.02.1996, p. 2564-2566.

Research output: Contribution to journalArticle

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