Behavior of Leishmania braziliensis s.l. in golden hamsters

Evolution of the infection under different experimental conditions

Bruno Travi, J. Rey-Ladino, N. G. Saravia

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Reproducibility of Leishmania braziliensis s.l. metastatic behavior in hamsters was studied for 9 isolates of L. b. panamensis and 2 of L. b. guyanensis with a previous record of metastasis. Also, the influence of corticosteroids and trauma was evaluated. In the corticosteroid-treated group, metastases appeared earlier than in the nontreated group, and localization at the site of trauma was more frequent (4/9) than in the nontreated hamsters (1/5). Nine of the 11 strains (82%) were capable of reproducing metastatic behavior. Studies on dissemination of L. b. panamensis showed that the regional lymph node is invaded as soon as 5 days postinfection, with further nonhematic dissemination to other tissues and organs in less than 4 wk.

Original languageEnglish (US)
Pages (from-to)1059-1062
Number of pages4
JournalJournal of Parasitology
Volume74
Issue number6
StatePublished - 1988
Externally publishedYes

Fingerprint

Leishmania braziliensis
Mesocricetus
adrenal cortex hormones
hamsters
metastasis
Cricetinae
Adrenal Cortex Hormones
Neoplasm Metastasis
Wounds and Injuries
Infection
infection
reproducibility
lymph nodes
Lymph Nodes
Mesocricetus auratus

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Microbiology
  • Parasitology

Cite this

Behavior of Leishmania braziliensis s.l. in golden hamsters : Evolution of the infection under different experimental conditions. / Travi, Bruno; Rey-Ladino, J.; Saravia, N. G.

In: Journal of Parasitology, Vol. 74, No. 6, 1988, p. 1059-1062.

Research output: Contribution to journalArticle

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