Abstract
Reproducibility of Leishmania braziliensis s.l. metastatic behavior in hamsters was studied for 9 isolates of L. b. panamensis and 2 of L. b. guyanensis with a previous record of metastasis. Also, the influence of corticosteroids and trauma was evaluated. In the corticosteroid-treated group, metastases appeared earlier than in the nontreated group, and localization at the site of trauma was more frequent (4/9) than in the nontreated hamsters (1/5). Nine of the 11 strains (82%) were capable of reproducing metastatic behavior. Studies on dissemination of L. b. panamensis showed that the regional lymph node is invaded as soon as 5 days postinfection, with further nonhematic dissemination to other tissues and organs in less than 4 wk.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1059-1062 |
| Number of pages | 4 |
| Journal | Journal of Parasitology |
| Volume | 74 |
| Issue number | 6 |
| DOIs | |
| State | Published - 1988 |
| Externally published | Yes |
ASJC Scopus subject areas
- Parasitology
- Ecology, Evolution, Behavior and Systematics
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