Binding and entering: COVID finds a new home

Michelle N. Vu, Vineet D. Menachery

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) emerged as a virus with a pathogenicity closer to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and a transmissibility similar to common cold coronaviruses (CoVs). In this review, we briefly discuss the features of the receptor-binding domain (RBD) and protease cleavage of the SARS-CoV-2 spike protein that enable SARS-CoV-2 to be a pandemic virus.

Original languageEnglish (US)
Article numbere1009857
JournalPLoS pathogens
Volume17
Issue number8
DOIs
StatePublished - Aug 2021

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Molecular Biology
  • Genetics
  • Virology

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