Binding of benzo(a)pyrene to rat lung glutathione S-transferases in vivo

Shivendra V. Singh; Satish K. Srivastava; Yogesh C. Awasthi

doi:10.1016/0014-5793(85)80202-7

Binding of benzo(a)pyrene to rat lung glutathione S-transferases in vivo

Shivendra V. Singh, Satish K. Srivastava, Yogesh C. Awasthi

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

A highly selective in vivo binding of benzo(a)pyrene to rat lung glutathione S-transferases is demonstrated. Benzo(a)pyrene or its metabolites are specifically bound to Ya' and Yc subunits of rat lung glutathione S-transferases.

Original language	English (US)
Pages (from-to)	111-114
Number of pages	4
Journal	FEBS Letters
Volume	179
Issue number	1
DOIs	https://doi.org/10.1016/0014-5793(85)80202-7
State	Published - Jan 1 1985
Externally published	Yes

Keywords

Benzo(a)pyrene
Glutathione S-transferase
Lung
Poly cyclic aromatic hydrocarbon Detoxifcation
Subunit

ASJC Scopus subject areas

Biophysics
Structural Biology
Biochemistry
Molecular Biology
Genetics
Cell Biology

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10.1016/0014-5793(85)80202-7

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title = "Binding of benzo(a)pyrene to rat lung glutathione S-transferases in vivo",

abstract = "A highly selective in vivo binding of benzo(a)pyrene to rat lung glutathione S-transferases is demonstrated. Benzo(a)pyrene or its metabolites are specifically bound to Ya' and Yc subunits of rat lung glutathione S-transferases.",

keywords = "Benzo(a)pyrene, Glutathione S-transferase, Lung, Poly cyclic aromatic hydrocarbon Detoxifcation, Subunit",

author = "Singh, {Shivendra V.} and Srivastava, {Satish K.} and Awasthi, {Yogesh C.}",

note = "Funding Information: This investigationw as supportedb y PHS grant CA 27967,a wardedb y the National Cancer Institute, grants EY 04396a nd EY 01677,a warded by the National Eye Institute, and grant GM 32304, awarded by Institute of General Medical Sciences.",

year = "1985",

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doi = "10.1016/0014-5793(85)80202-7",

language = "English (US)",

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pages = "111--114",

journal = "FEBS Letters",

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T1 - Binding of benzo(a)pyrene to rat lung glutathione S-transferases in vivo

AU - Singh, Shivendra V.

AU - Srivastava, Satish K.

AU - Awasthi, Yogesh C.

N1 - Funding Information: This investigationw as supportedb y PHS grant CA 27967,a wardedb y the National Cancer Institute, grants EY 04396a nd EY 01677,a warded by the National Eye Institute, and grant GM 32304, awarded by Institute of General Medical Sciences.

PY - 1985/1/1

Y1 - 1985/1/1

N2 - A highly selective in vivo binding of benzo(a)pyrene to rat lung glutathione S-transferases is demonstrated. Benzo(a)pyrene or its metabolites are specifically bound to Ya' and Yc subunits of rat lung glutathione S-transferases.

AB - A highly selective in vivo binding of benzo(a)pyrene to rat lung glutathione S-transferases is demonstrated. Benzo(a)pyrene or its metabolites are specifically bound to Ya' and Yc subunits of rat lung glutathione S-transferases.

KW - Benzo(a)pyrene

KW - Glutathione S-transferase

KW - Lung

KW - Poly cyclic aromatic hydrocarbon Detoxifcation

KW - Subunit

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SP - 111

EP - 114

JO - FEBS Letters

JF - FEBS Letters

IS - 1

ER -

Binding of benzo(a)pyrene to rat lung glutathione S-transferases in vivo

Abstract

Keywords

ASJC Scopus subject areas

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