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Binding of LcrV protein from Yersinia pestis to human T-cells induces apoptosis, which is completely blocked by specific antibodies
Vyacheslav M. Abramov
, Igor V. Kosarev
,
Vladimir L. Motin
, Valentin S. Khlebnikov
, Raisa N. Vasilenko
, Vadim K. Sakulin
, Andrey V. Machulin
, Vladimir N. Uversky
, Andrey V. Karlyshev
Pathology
Research output
:
Contribution to journal
›
Article
›
peer-review
7
Scopus citations
Overview
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Keyphrases
T Cells
100%
Induced Apoptosis
100%
Specific Antibodies
100%
Yersinia Pestis
100%
LcrV
100%
Interferon-α (IFN-α)
70%
Plague
30%
Thymocytes
20%
Homodimer
20%
Jurkat T Cells
20%
Apoptosis
10%
Host Cell
10%
Monoclonal Antibody
10%
Specific Interactions
10%
C-terminal Region
10%
Interferon Receptor
10%
V Antigen
10%
High-affinity Binding
10%
Toll-like Receptor 2 (TLR2)
10%
IL-10 Production
10%
Severe Symptoms
10%
Immobilization
10%
Leukemia Cells
10%
Jurkat
10%
Protective Proteins
10%
Vaccine Components
10%
T Leukemia
10%
Human Thymocytes
10%
Immunology and Microbiology
T Cell
100%
Yersinia Pestis
100%
LcrV
100%
Programmed Cell Death
100%
Human Interferon
80%
Thymocyte
30%
Binding Affinity
10%
Host Cell
10%
Monoclonal Antibody
10%
Interleukin 10
10%
Carboxy Terminal Sequence
10%
Leukemia Cell
10%
TLR2
10%