Biomarkers in asthma

Anandhi Murugan, Curig Prys-Picard, William J. Calhoun

Research output: Contribution to journalReview articlepeer-review

36 Scopus citations

Abstract

To date, the best validated, and best performing biomarkers for clinical asthma appear to be measures of inflammation in induced sputum, and measures of ENO. Some trials using ENO appear particularly promising for early clinical use. EBC metrics are at present too inchoate for clinical purposes. However, not all important clinical and research questions can be addressed with sputum, EBC, or ENO metrics, leaving an important place for BAL, bronchial biopsy, and perhaps EBC measurements in the research arena.

Original languageEnglish (US)
Pages (from-to)12-18
Number of pages7
JournalCurrent Opinion in Pulmonary Medicine
Volume15
Issue number1
DOIs
StatePublished - Jan 2009

Keywords

  • Asthma
  • Biomarker
  • Phenotype
  • Prediction

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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