Neonatal sepsis is an important cause of morbidity and mortality in infants, and diagnosis of neonatal sepsis remains challenging. The diagnostic standard for neonatal sepsis is blood culture. Sensitivity of blood culture may be affected by antepartum antibiotic exposure or volume of blood collected for culture. The present review highlights the importance of various biomarkers that can be used in combination with hematologic scoring to diagnose neonatal sepsis.
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