Biosynthetic skin substitute versus frozen human cadaver allograft for temporary coverage of excised burn wounds

G. F. Purdue, J. L. Hunt, R. W. Gillespie, J. F. Hansbrough, W. J. Dominic, M. C. Robson, D. J. Smith, B. G. MacMillan, J. P. Waymac, David Herndon

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Abstract

During the past 2 years a multicenter study was performed comparing Biobrane (Woodroof) and frozen cadaver allograft as temporary dressings on freshly excised full-thickness burns before the application of autograft. Each biologic dressing was evaluated with respect to the other on the same patient. Seventy-one patients were evaluated. The mean burn size was 35 ± 20% with a mean full-thickness burn of 28 ± 20%. Mean patient age was 34 ± 21 years. Overall survival was 82%. The mean time of wound coverage was 10.2 ± 6.7 years. There was no significant difference in the number of dressing changes, area changed, purulence, autograft take, and final results between allograft- and Biobrane-covered sites. There were no complications following use of either Biobrane or allograft. We conclude that Biobrane is as effective as frozen human cadaver allograft for the temporary coverage of freshly excised full-thickness burn wounds before autografting.

Original languageEnglish (US)
Pages (from-to)155-157
Number of pages3
JournalJournal of Trauma
Volume27
Issue number2
StatePublished - 1987

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Artificial Skin
Cadaver
Allografts
Autografts
Wounds and Injuries
Bandages
Biological Dressings
Autologous Transplantation
Burns
Multicenter Studies
Survival
Biobrane

ASJC Scopus subject areas

  • Surgery

Cite this

Purdue, G. F., Hunt, J. L., Gillespie, R. W., Hansbrough, J. F., Dominic, W. J., Robson, M. C., ... Herndon, D. (1987). Biosynthetic skin substitute versus frozen human cadaver allograft for temporary coverage of excised burn wounds. Journal of Trauma, 27(2), 155-157.

Biosynthetic skin substitute versus frozen human cadaver allograft for temporary coverage of excised burn wounds. / Purdue, G. F.; Hunt, J. L.; Gillespie, R. W.; Hansbrough, J. F.; Dominic, W. J.; Robson, M. C.; Smith, D. J.; MacMillan, B. G.; Waymac, J. P.; Herndon, David.

In: Journal of Trauma, Vol. 27, No. 2, 1987, p. 155-157.

Research output: Contribution to journalArticle

Purdue, GF, Hunt, JL, Gillespie, RW, Hansbrough, JF, Dominic, WJ, Robson, MC, Smith, DJ, MacMillan, BG, Waymac, JP & Herndon, D 1987, 'Biosynthetic skin substitute versus frozen human cadaver allograft for temporary coverage of excised burn wounds', Journal of Trauma, vol. 27, no. 2, pp. 155-157.
Purdue GF, Hunt JL, Gillespie RW, Hansbrough JF, Dominic WJ, Robson MC et al. Biosynthetic skin substitute versus frozen human cadaver allograft for temporary coverage of excised burn wounds. Journal of Trauma. 1987;27(2):155-157.
Purdue, G. F. ; Hunt, J. L. ; Gillespie, R. W. ; Hansbrough, J. F. ; Dominic, W. J. ; Robson, M. C. ; Smith, D. J. ; MacMillan, B. G. ; Waymac, J. P. ; Herndon, David. / Biosynthetic skin substitute versus frozen human cadaver allograft for temporary coverage of excised burn wounds. In: Journal of Trauma. 1987 ; Vol. 27, No. 2. pp. 155-157.
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