Black Tea Improves Endothelial Function in Renal Transplant Recipients

M. R. Ardalan, M. K. Tarzamni, Mohammadali Mohajel Shoja, R. S. Tubbs, B. Rahimi-Ardabili, K. Ghabili, H. T. Khosroshahi

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Background: Endothelial damage and dysfunction are commonplace in renal transplant recipients. Impaired endothelial function is an important contributor to cardiovascular diseases. We hypothesized that short-term black tea consumption may improve endothelium-dependent arterial dilation in kidney recipients. Methods: Fifteen recipients were studied on an outpatient basis in a single, university-affiliated clinic. Inclusion criteria were stable and good allograft function. The main exclusion criteria were uncontrolled hypertension, smoking, alcohol consumption, coffee drinking, diabetes mellitus, and coronary artery disease, or a history of upper limb vascular manipulations. After overnight fasting, the brachial artery diameter (BAD) was measured at the end of diastole using an ultrasound machine before (basal BAD) and 1 minute after temporary (∼3 minutes) external occlusion (posthyperemia BAD). Flow-mediated vasodilation (FMV) and percent of FMV (FMV%) were calculated by appropriate formula. FMV and FMV% were determined at baseline and 2 hours after consuming 0.5 L freshly brewed black tea. For control, the study was repeated for each patient the next day and FMV and FMV% were determined before and 2 hours after consuming 0.5 L of water. Results: The men age of patients was 37.2 ± 9.7 years (range, 25 to 50) with a male:female ratio of 3:2. Patients were 26.8 ± 10.6 months postrenal transplantation. Black tea consumption significantly increased posthyperemia BAD, FMV, and FMV% (P < .05). However, water consumption did not alter the basal or posthyperemia BAD, FMV, or FMV% (P > .05). Conclusion: Based on our study, short-term consumption of black tea may improve endothelial function and endothelium-dependent arterial vasodilation in renal transplant recipients.

Original languageEnglish (US)
Pages (from-to)1139-1142
Number of pages4
JournalTransplantation Proceedings
Volume39
Issue number4
DOIs
StatePublished - May 1 2007
Externally publishedYes

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Tea
Vasodilation
Kidney
Brachial Artery
Endothelium
Transplant Recipients
Diastole
Coffee
Upper Extremity
Alcohol Drinking
Drinking
Allografts
Blood Vessels
Coronary Artery Disease
Dilatation
Fasting
Diabetes Mellitus
Outpatients
Cardiovascular Diseases
Transplantation

ASJC Scopus subject areas

  • Surgery
  • Transplantation

Cite this

Ardalan, M. R., Tarzamni, M. K., Mohajel Shoja, M., Tubbs, R. S., Rahimi-Ardabili, B., Ghabili, K., & Khosroshahi, H. T. (2007). Black Tea Improves Endothelial Function in Renal Transplant Recipients. Transplantation Proceedings, 39(4), 1139-1142. https://doi.org/10.1016/j.transproceed.2007.04.010

Black Tea Improves Endothelial Function in Renal Transplant Recipients. / Ardalan, M. R.; Tarzamni, M. K.; Mohajel Shoja, Mohammadali; Tubbs, R. S.; Rahimi-Ardabili, B.; Ghabili, K.; Khosroshahi, H. T.

In: Transplantation Proceedings, Vol. 39, No. 4, 01.05.2007, p. 1139-1142.

Research output: Contribution to journalArticle

Ardalan, MR, Tarzamni, MK, Mohajel Shoja, M, Tubbs, RS, Rahimi-Ardabili, B, Ghabili, K & Khosroshahi, HT 2007, 'Black Tea Improves Endothelial Function in Renal Transplant Recipients', Transplantation Proceedings, vol. 39, no. 4, pp. 1139-1142. https://doi.org/10.1016/j.transproceed.2007.04.010
Ardalan MR, Tarzamni MK, Mohajel Shoja M, Tubbs RS, Rahimi-Ardabili B, Ghabili K et al. Black Tea Improves Endothelial Function in Renal Transplant Recipients. Transplantation Proceedings. 2007 May 1;39(4):1139-1142. https://doi.org/10.1016/j.transproceed.2007.04.010
Ardalan, M. R. ; Tarzamni, M. K. ; Mohajel Shoja, Mohammadali ; Tubbs, R. S. ; Rahimi-Ardabili, B. ; Ghabili, K. ; Khosroshahi, H. T. / Black Tea Improves Endothelial Function in Renal Transplant Recipients. In: Transplantation Proceedings. 2007 ; Vol. 39, No. 4. pp. 1139-1142.
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abstract = "Background: Endothelial damage and dysfunction are commonplace in renal transplant recipients. Impaired endothelial function is an important contributor to cardiovascular diseases. We hypothesized that short-term black tea consumption may improve endothelium-dependent arterial dilation in kidney recipients. Methods: Fifteen recipients were studied on an outpatient basis in a single, university-affiliated clinic. Inclusion criteria were stable and good allograft function. The main exclusion criteria were uncontrolled hypertension, smoking, alcohol consumption, coffee drinking, diabetes mellitus, and coronary artery disease, or a history of upper limb vascular manipulations. After overnight fasting, the brachial artery diameter (BAD) was measured at the end of diastole using an ultrasound machine before (basal BAD) and 1 minute after temporary (∼3 minutes) external occlusion (posthyperemia BAD). Flow-mediated vasodilation (FMV) and percent of FMV (FMV{\%}) were calculated by appropriate formula. FMV and FMV{\%} were determined at baseline and 2 hours after consuming 0.5 L freshly brewed black tea. For control, the study was repeated for each patient the next day and FMV and FMV{\%} were determined before and 2 hours after consuming 0.5 L of water. Results: The men age of patients was 37.2 ± 9.7 years (range, 25 to 50) with a male:female ratio of 3:2. Patients were 26.8 ± 10.6 months postrenal transplantation. Black tea consumption significantly increased posthyperemia BAD, FMV, and FMV{\%} (P < .05). However, water consumption did not alter the basal or posthyperemia BAD, FMV, or FMV{\%} (P > .05). Conclusion: Based on our study, short-term consumption of black tea may improve endothelial function and endothelium-dependent arterial vasodilation in renal transplant recipients.",
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AU - Tarzamni, M. K.

AU - Mohajel Shoja, Mohammadali

AU - Tubbs, R. S.

AU - Rahimi-Ardabili, B.

AU - Ghabili, K.

AU - Khosroshahi, H. T.

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N2 - Background: Endothelial damage and dysfunction are commonplace in renal transplant recipients. Impaired endothelial function is an important contributor to cardiovascular diseases. We hypothesized that short-term black tea consumption may improve endothelium-dependent arterial dilation in kidney recipients. Methods: Fifteen recipients were studied on an outpatient basis in a single, university-affiliated clinic. Inclusion criteria were stable and good allograft function. The main exclusion criteria were uncontrolled hypertension, smoking, alcohol consumption, coffee drinking, diabetes mellitus, and coronary artery disease, or a history of upper limb vascular manipulations. After overnight fasting, the brachial artery diameter (BAD) was measured at the end of diastole using an ultrasound machine before (basal BAD) and 1 minute after temporary (∼3 minutes) external occlusion (posthyperemia BAD). Flow-mediated vasodilation (FMV) and percent of FMV (FMV%) were calculated by appropriate formula. FMV and FMV% were determined at baseline and 2 hours after consuming 0.5 L freshly brewed black tea. For control, the study was repeated for each patient the next day and FMV and FMV% were determined before and 2 hours after consuming 0.5 L of water. Results: The men age of patients was 37.2 ± 9.7 years (range, 25 to 50) with a male:female ratio of 3:2. Patients were 26.8 ± 10.6 months postrenal transplantation. Black tea consumption significantly increased posthyperemia BAD, FMV, and FMV% (P < .05). However, water consumption did not alter the basal or posthyperemia BAD, FMV, or FMV% (P > .05). Conclusion: Based on our study, short-term consumption of black tea may improve endothelial function and endothelium-dependent arterial vasodilation in renal transplant recipients.

AB - Background: Endothelial damage and dysfunction are commonplace in renal transplant recipients. Impaired endothelial function is an important contributor to cardiovascular diseases. We hypothesized that short-term black tea consumption may improve endothelium-dependent arterial dilation in kidney recipients. Methods: Fifteen recipients were studied on an outpatient basis in a single, university-affiliated clinic. Inclusion criteria were stable and good allograft function. The main exclusion criteria were uncontrolled hypertension, smoking, alcohol consumption, coffee drinking, diabetes mellitus, and coronary artery disease, or a history of upper limb vascular manipulations. After overnight fasting, the brachial artery diameter (BAD) was measured at the end of diastole using an ultrasound machine before (basal BAD) and 1 minute after temporary (∼3 minutes) external occlusion (posthyperemia BAD). Flow-mediated vasodilation (FMV) and percent of FMV (FMV%) were calculated by appropriate formula. FMV and FMV% were determined at baseline and 2 hours after consuming 0.5 L freshly brewed black tea. For control, the study was repeated for each patient the next day and FMV and FMV% were determined before and 2 hours after consuming 0.5 L of water. Results: The men age of patients was 37.2 ± 9.7 years (range, 25 to 50) with a male:female ratio of 3:2. Patients were 26.8 ± 10.6 months postrenal transplantation. Black tea consumption significantly increased posthyperemia BAD, FMV, and FMV% (P < .05). However, water consumption did not alter the basal or posthyperemia BAD, FMV, or FMV% (P > .05). Conclusion: Based on our study, short-term consumption of black tea may improve endothelial function and endothelium-dependent arterial vasodilation in renal transplant recipients.

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