Bladder reconstruction in rabbits with glutaraldehyde-stablilized amniotic membranes

Mark A. Norris, Marc S. Cohen, Michael M. Warren, Steven N. Becker, Paul S. Baur, Herbert M. Seybold

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Glutaraldehyde-treated human amniotic membranes were used to repair rabbit bladders after supratrigonal cystectomies. The membranes maintained the integrity of the bladders until healing and reepithelialization occurred. There was no significant loss of bladder capacity or decreased renal function postoperatively. Calcification did not occur on the membranes but was noted on chromic sutures retaining the membranes in 7 of 27 bladders. These findings suggest that glutaraldehyde-stabilized amnion is well tolerated by the urothelium and may serve as a suitable material for replacement of genitourinary tissues.

Original languageEnglish (US)
Pages (from-to)631-635
Number of pages5
JournalUrology
Volume19
Issue number6
DOIs
StatePublished - Jun 1982

ASJC Scopus subject areas

  • Urology

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    Norris, M. A., Cohen, M. S., Warren, M. M., Becker, S. N., Baur, P. S., & Seybold, H. M. (1982). Bladder reconstruction in rabbits with glutaraldehyde-stablilized amniotic membranes. Urology, 19(6), 631-635. https://doi.org/10.1016/0090-4295(82)90017-6