Blood lead, calcium status, and behavior in preschool children

D. Laraque, M. McCormick, M. Norman, A. Taylor, Susan Weller, J. Karp

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

To determine if calcium status is associated with blood lead levels and behavior, 64 black urban children aged 18 to 47 months were studied. Twenty-seven controls (blood lead levels, < 1.45 μmol/L) were compared with 37 cases (blood lead levels ≥ 1.45 μmol/L) with respect to four calcium measures (calcium intake, serum calcium level, 1,25-dihydroxyvitamin D level, and bone densitometric findings) and three behavioral scores. Levels of 25-hydroxyvitamin D provided a measure of vitamin D sufficiency. As expected, blood lead level was associated with pica scores. However, none of the calcium measures differed between cases and controls. Controlling for four confounders (season, pica score,maternal education, and sex), yielded no significant differences between the two groups in the mean values of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D level. There was no interaction between blood lead level and the four covariates. No relationship could be demonstrated between calcium status and the pica scores.

Original languageEnglish (US)
Pages (from-to)186-189
Number of pages4
JournalAmerican Journal of Diseases of Children
Volume144
Issue number2
StatePublished - 1990

Fingerprint

Preschool Children
Pica
Calcium
Sex Education
Vitamin D
Lead
Mothers
Bone and Bones
Serum

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Laraque, D., McCormick, M., Norman, M., Taylor, A., Weller, S., & Karp, J. (1990). Blood lead, calcium status, and behavior in preschool children. American Journal of Diseases of Children, 144(2), 186-189.

Blood lead, calcium status, and behavior in preschool children. / Laraque, D.; McCormick, M.; Norman, M.; Taylor, A.; Weller, Susan; Karp, J.

In: American Journal of Diseases of Children, Vol. 144, No. 2, 1990, p. 186-189.

Research output: Contribution to journalArticle

Laraque, D, McCormick, M, Norman, M, Taylor, A, Weller, S & Karp, J 1990, 'Blood lead, calcium status, and behavior in preschool children', American Journal of Diseases of Children, vol. 144, no. 2, pp. 186-189.
Laraque D, McCormick M, Norman M, Taylor A, Weller S, Karp J. Blood lead, calcium status, and behavior in preschool children. American Journal of Diseases of Children. 1990;144(2):186-189.
Laraque, D. ; McCormick, M. ; Norman, M. ; Taylor, A. ; Weller, Susan ; Karp, J. / Blood lead, calcium status, and behavior in preschool children. In: American Journal of Diseases of Children. 1990 ; Vol. 144, No. 2. pp. 186-189.
@article{ed4d087d91884250893d0bee59d01d64,
title = "Blood lead, calcium status, and behavior in preschool children",
abstract = "To determine if calcium status is associated with blood lead levels and behavior, 64 black urban children aged 18 to 47 months were studied. Twenty-seven controls (blood lead levels, < 1.45 μmol/L) were compared with 37 cases (blood lead levels ≥ 1.45 μmol/L) with respect to four calcium measures (calcium intake, serum calcium level, 1,25-dihydroxyvitamin D level, and bone densitometric findings) and three behavioral scores. Levels of 25-hydroxyvitamin D provided a measure of vitamin D sufficiency. As expected, blood lead level was associated with pica scores. However, none of the calcium measures differed between cases and controls. Controlling for four confounders (season, pica score,maternal education, and sex), yielded no significant differences between the two groups in the mean values of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D level. There was no interaction between blood lead level and the four covariates. No relationship could be demonstrated between calcium status and the pica scores.",
author = "D. Laraque and M. McCormick and M. Norman and A. Taylor and Susan Weller and J. Karp",
year = "1990",
language = "English (US)",
volume = "144",
pages = "186--189",
journal = "JAMA Pediatrics",
issn = "2168-6203",
publisher = "American Medical Association",
number = "2",

}

TY - JOUR

T1 - Blood lead, calcium status, and behavior in preschool children

AU - Laraque, D.

AU - McCormick, M.

AU - Norman, M.

AU - Taylor, A.

AU - Weller, Susan

AU - Karp, J.

PY - 1990

Y1 - 1990

N2 - To determine if calcium status is associated with blood lead levels and behavior, 64 black urban children aged 18 to 47 months were studied. Twenty-seven controls (blood lead levels, < 1.45 μmol/L) were compared with 37 cases (blood lead levels ≥ 1.45 μmol/L) with respect to four calcium measures (calcium intake, serum calcium level, 1,25-dihydroxyvitamin D level, and bone densitometric findings) and three behavioral scores. Levels of 25-hydroxyvitamin D provided a measure of vitamin D sufficiency. As expected, blood lead level was associated with pica scores. However, none of the calcium measures differed between cases and controls. Controlling for four confounders (season, pica score,maternal education, and sex), yielded no significant differences between the two groups in the mean values of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D level. There was no interaction between blood lead level and the four covariates. No relationship could be demonstrated between calcium status and the pica scores.

AB - To determine if calcium status is associated with blood lead levels and behavior, 64 black urban children aged 18 to 47 months were studied. Twenty-seven controls (blood lead levels, < 1.45 μmol/L) were compared with 37 cases (blood lead levels ≥ 1.45 μmol/L) with respect to four calcium measures (calcium intake, serum calcium level, 1,25-dihydroxyvitamin D level, and bone densitometric findings) and three behavioral scores. Levels of 25-hydroxyvitamin D provided a measure of vitamin D sufficiency. As expected, blood lead level was associated with pica scores. However, none of the calcium measures differed between cases and controls. Controlling for four confounders (season, pica score,maternal education, and sex), yielded no significant differences between the two groups in the mean values of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D level. There was no interaction between blood lead level and the four covariates. No relationship could be demonstrated between calcium status and the pica scores.

UR - http://www.scopus.com/inward/record.url?scp=0025058878&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025058878&partnerID=8YFLogxK

M3 - Article

VL - 144

SP - 186

EP - 189

JO - JAMA Pediatrics

JF - JAMA Pediatrics

SN - 2168-6203

IS - 2

ER -